Protein Info for TX73_010595 in Rhodopseudomonas palustris CGA009

Annotation: efflux RND transporter periplasmic adaptor subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 331 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF16576: HlyD_D23" amino acids 137 to 246 (110 residues), 76.3 bits, see alignment E=3.3e-25 TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 138 to 309 (172 residues), 96.9 bits, see alignment E=5.5e-32 PF13437: HlyD_3" amino acids 144 to 241 (98 residues), 52.8 bits, see alignment E=8.8e-18

Best Hits

KEGG orthology group: None (inferred from 100% identity to rpt:Rpal_2345)

Predicted SEED Role

"Cobalt/zinc/cadmium efflux RND transporter, membrane fusion protein, CzcB family" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (331 amino acids)

>TX73_010595 efflux RND transporter periplasmic adaptor subunit (Rhodopseudomonas palustris CGA009)
MMKPLMLICGAAAMFALGAAVSAYAPIGSREPAQQAGKDPKGHNHAAGEKGHDHGGHDEE
GAVEMSDAKVAASGIEIRTAKAETLHESLVLNGILQPNQETLVQVTPRFPGVVREIRKRI
GDTVEKGELLAKIESNQSLSVYEMRAPISGTVIDRQISLGEYASEQKPAFTVADVSTVWV
DLSVHRRDLPRVRIGDKILIDVADGGQPIEASLSYISPVGSSDTQSALARAVVPNDAMRL
RSGLFVSARLILSAKPVPLAVRASAIQTVENRSVVFVRSGDKFEVRDVELGARDAENVEI
VFGLLDGDRYAAANSFVVKAELGKGSASHEH