Protein Info for TX73_010140 in Rhodopseudomonas palustris CGA009

Annotation: efflux RND transporter periplasmic adaptor subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 371 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 42 to 360 (319 residues), 225.6 bits, see alignment E=3.9e-71 PF16576: HlyD_D23" amino acids 70 to 279 (210 residues), 62.3 bits, see alignment E=6.1e-21 PF13533: Biotin_lipoyl_2" amino acids 72 to 113 (42 residues), 32.8 bits, see alignment 7e-12 PF13437: HlyD_3" amino acids 177 to 272 (96 residues), 39.3 bits, see alignment E=1.3e-13

Best Hits

KEGG orthology group: None (inferred from 100% identity to rpa:RPA1967)

Predicted SEED Role

"Probable Co/Zn/Cd efflux system membrane fusion protein" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (371 amino acids)

>TX73_010140 efflux RND transporter periplasmic adaptor subunit (Rhodopseudomonas palustris CGA009)
MREIVGFRSAIIAMALILGGCDSATPKPDRGGKEPRKAQPVMVVPVRFEEGARTRTFAAT
IRPSIESDLGFRISGKVARRLVRTGDLVRSGQALLTLDTNDLRLQREQAEAEVKAAQSNL
IQAEADEGRAVELQSKGWMANAALQKAHATAEEARSRLIRAQRALDLAGHALGYATLEAD
ADGVITATPIEPGQVISAGQAAVRLARLSELEAVVALPESYVERVGRASASLSLWSLPGK
TYDARLRELSFAADLATRTFAARFVIPGADDKVRIGMSATLTLREQDERRFARLPLTAVY
NHGRGAAVFVVGDGGELHERPVTIERYEDRNVLVTSGVSDGETVVALGVEKLDPALTVRP
ISTLSLSSAGK