Protein Info for TX73_010135 in Rhodopseudomonas palustris CGA009

Annotation: TetR/AcrR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 210 PF00440: TetR_N" amino acids 13 to 58 (46 residues), 63.8 bits, see alignment 9.9e-22 PF14246: TetR_C_7" amino acids 86 to 202 (117 residues), 103.6 bits, see alignment E=7.1e-34

Best Hits

KEGG orthology group: None (inferred from 100% identity to rpa:RPA1966)

Predicted SEED Role

"Transcription regulator of multidrug efflux pump operon, TetR (AcrR) family" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (210 amino acids)

>TX73_010135 TetR/AcrR family transcriptional regulator (Rhodopseudomonas palustris CGA009)
MVRVRTEAKRDAILDTAAEVFKERGLEGASMSEIASRLGGSKATLYGYFPSKEDLFVHVA
LRVAGKQILGMYEDLEARAADDPERVLTEVGKKLLKRVLAEDATTANRLAVAHGRIGNLG
RIFYDAGPGKAIEAFTRYIDAATKAGRLRADHPGAAAHHLLALLESEIAYRRRLQFDDAI
SASEIDQCVGRAVTVFLAAYAAPRTSDKAS