Protein Info for TX73_010130 in Rhodopseudomonas palustris CGA009

Annotation: adenylate/guanylate cyclase domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 662 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 304 to 326 (23 residues), see Phobius details PF00672: HAMP" amino acids 323 to 374 (52 residues), 29.4 bits, see alignment 7.9e-11 PF00211: Guanylate_cyc" amino acids 432 to 611 (180 residues), 99.2 bits, see alignment E=2.4e-32

Best Hits

KEGG orthology group: None (inferred from 100% identity to rpa:RPA1965)

Predicted SEED Role

"Adenylate cyclase (EC 4.6.1.1)" in subsystem cAMP signaling in bacteria (EC 4.6.1.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.6.1.1

Use Curated BLAST to search for 4.6.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (662 amino acids)

>TX73_010130 adenylate/guanylate cyclase domain-containing protein (Rhodopseudomonas palustris CGA009)
MKFTTRLVLLVTVLTVGATLVTAALLTWTTRRAIITEAEASGEKVARLLARSASLAASIP
TEVEGIIAEEMTAEGTLLGHFVEAAERAGMTPTEINRRLKSITDDTVLDEIWITDEKGHA
YLHSLPDVNFTFSNSPQLQPQAYAFYDLLNGQKKVVNQDARKRDIDNQHFKYVGVGGIDK
PRIIQVGRSAKFLQQLTMKIGLPRTVENLLADGDIDAVWVFDRKLDALVGPGVYGADRRD
GPNEKELGPVRLVIADGQTRHVESRQNLSVIAPVRNDQKEIVGAALVRLPMNRVWATVQS
QAEIAAATASAIAALGILLSIGVARYQAAPLRQITRAAVALETQKFDPALLKPVSARRDE
LGQLARVFTGMAGQVAAREEYLDSMVKQRTEELETRNRSLEGLSAALSKYLSPQVYSSIF
SGHQDAEIASKRKKLTIFLSDIANFTATTDKLESEDLTAMLNRYLAEMAQIALKHGATID
KYVGDAVLAFFGDPDSRGVKEDAVACVMMAIEMQEKLKQLEMEWIDAGAERPFRVRIGIN
TGFCTVGNFGSPDRMDYTIVGGAVNLTSRLEQNCEPGSILISHVTWSLVNDVIDAEERPA
LTVKGFSEPVRAYEVRGLKTSGSTDVIRKELPGMRLFIDTVTADRTEVKQTLVQVVEDLD
KS