Protein Info for TX73_010060 in Rhodopseudomonas palustris CGA009

Annotation: HlyD family secretion protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 291 transmembrane" amino acids 7 to 29 (23 residues), see Phobius details PF16576: HlyD_D23" amino acids 46 to 240 (195 residues), 46.2 bits, see alignment E=5.3e-16 TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 46 to 243 (198 residues), 113 bits, see alignment E=7e-37 PF13533: Biotin_lipoyl_2" amino acids 48 to 94 (47 residues), 61 bits, see alignment 1.1e-20 PF13437: HlyD_3" amino acids 157 to 242 (86 residues), 43.2 bits, see alignment E=8.6e-15

Best Hits

Swiss-Prot: 40% identical to AAEA_YERPB: p-hydroxybenzoic acid efflux pump subunit AaeA (aaeA) from Yersinia pseudotuberculosis serotype IB (strain PB1/+)

KEGG orthology group: None (inferred from 100% identity to rpt:Rpal_2162)

Predicted SEED Role

"FIG01007522: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (291 amino acids)

>TX73_010060 HlyD family secretion protein (Rhodopseudomonas palustris CGA009)
MGKTPLLLIRLSVTTLGVLVAALIGWRLWVHYEIEPWTRDGRVRADIVAVAPDVSGLVSE
VLVVDNQVVKKGDILFRIDRERFTLALRQADAAVEGRVAALDAANKDLARYRNLSSDAVT
EQKREQITATQAEAEAALHQAIADRDIAKLNLDRSEVRAQVGGLITNFDLRPGAYVNAGS
GVAALIDQATLHVDGYFEETKLPSIRVGDRAEVRLMGERNPLSGHVQSIAGGIEDRDRSA
GAKLLPNVNPTFNWVRLAQRIPVRIALDHVPPEVRLVVGRTATVVIERRGG