Protein Info for TX73_009355 in Rhodopseudomonas palustris CGA009

Annotation: sigma-70 family RNA polymerase sigma factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 189 PF07638: Sigma70_ECF" amino acids 12 to 178 (167 residues), 30.4 bits, see alignment E=7.2e-11 TIGR02937: RNA polymerase sigma factor, sigma-70 family" amino acids 25 to 177 (153 residues), 106.3 bits, see alignment E=6.3e-35 PF04542: Sigma70_r2" amino acids 27 to 93 (67 residues), 59.4 bits, see alignment E=5e-20 PF08281: Sigma70_r4_2" amino acids 123 to 175 (53 residues), 56.4 bits, see alignment E=3.7e-19 PF04545: Sigma70_r4" amino acids 128 to 175 (48 residues), 49.7 bits, see alignment E=4.1e-17

Best Hits

KEGG orthology group: K03088, RNA polymerase sigma-70 factor, ECF subfamily (inferred from 100% identity to rpt:Rpal_2022)

Predicted SEED Role

"RNA polymerase sigma factor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (189 amino acids)

>TX73_009355 sigma-70 family RNA polymerase sigma factor (Rhodopseudomonas palustris CGA009)
MSTKQAATDDVLIARIAQGDRVAMQVLYGRHHVKVFRFGLRLVRNEQIAEDLISEVFLDV
WRQAGKFEGRSSVSTWLLAITRFKALSALRRRKDAELDDEAAAAIEDPSDDPEIAVQKKD
TGEALRKCLSSLTPEHREIVDLVYYHEKSIEEVAEIVGIPENTVKTRLFYARKKLADLLQ
AAGVQRGWP