Protein Info for TX73_009255 in Rhodopseudomonas palustris CGA009

Annotation: UdgX family uracil-DNA binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 495 TIGR03915: probable DNA metabolism protein" amino acids 7 to 254 (248 residues), 242.9 bits, see alignment E=6.1e-76 PF13566: DUF4130" amino acids 95 to 253 (159 residues), 147.7 bits, see alignment E=2.6e-47 TIGR03914: uracil-DNA glycosylase family domain" amino acids 256 to 485 (230 residues), 354.3 bits, see alignment E=4.6e-110 TIGR00758: uracil-DNA glycosylase, family 4" amino acids 309 to 473 (165 residues), 138.4 bits, see alignment E=3.1e-44 PF03167: UDG" amino acids 323 to 483 (161 residues), 116.2 bits, see alignment E=1.3e-37

Best Hits

KEGG orthology group: K02334, DNA polymerase bacteriophage-type [EC: 2.7.7.7] (inferred from 100% identity to rpa:RPA1799)

Predicted SEED Role

"Domain often clustered or fused with uracil-DNA glycosylase / Uracil-DNA glycosylase, putative family 6"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (495 amino acids)

>TX73_009255 UdgX family uracil-DNA binding protein (Rhodopseudomonas palustris CGA009)
MNRIRLDSDTDFDGWRKAARELVLADVAPADVTWTVAGDEPELFDVAGLAPHAGTFAEMA
APFIHPAQSPSPAQTFNVPARFVELAHIAILHRDPQRFAYLYQLLWRLRANPELMQVATD
PDVARLQAMAKAVRRDEHKMHAFVRFREIGREPKSRYVAWFEPEHHIVELAAPFFARRFA
DMEWSILTPDACAHWDGHAIAITPGVSKAMAPSEDRLEETWLTYYASIFNPARLKTRAMQ
AEMPKKYWRNLPEAALIKPLIEHAERKAHAMVAAEATAPRKPQRQEPPMTRAEPKADTLA
HLREEAKDCRACDLWKDATQTVFGEGPQHATVMLVGEQPGDKEDLAGQPFVGPAGQMLDR
ALAEAGVDRSKTYVTNAVKHFKFVPRGKIRLHQKPATPEIKACRQWYERELAAVQPLLVV
AMGATAAQSVLGRITPINKTRGHLIDRDDGPQVLVTVHPSYLLRLPDADAKAREYARFVE
DLKLIAAHLKKAHAA