Protein Info for TX73_009065 in Rhodopseudomonas palustris CGA009
Annotation: fatty acid--CoA ligase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00666, fatty-acyl-CoA synthase [EC: 6.2.1.-] (inferred from 100% identity to rpa:RPA1763)Predicted SEED Role
"O-succinylbenzoic acid--CoA ligase (EC 6.2.1.26)" in subsystem Menaquinone and Phylloquinone Biosynthesis (EC 6.2.1.26)
MetaCyc Pathways
- 2-carboxy-1,4-naphthoquinol biosynthesis (3/7 steps found)
- superpathway of menaquinol-10 biosynthesis (5/10 steps found)
- superpathway of menaquinol-8 biosynthesis I (5/10 steps found)
- superpathway of menaquinol-9 biosynthesis (5/10 steps found)
- superpathway of chorismate metabolism (40/59 steps found)
- superpathway of demethylmenaquinol-8 biosynthesis I (4/9 steps found)
- superpathway of demethylmenaquinol-9 biosynthesis (4/9 steps found)
- superpathway of menaquinol-11 biosynthesis (4/10 steps found)
- superpathway of menaquinol-12 biosynthesis (4/10 steps found)
- superpathway of menaquinol-13 biosynthesis (4/10 steps found)
- superpathway of menaquinol-6 biosynthesis (4/10 steps found)
- superpathway of menaquinol-7 biosynthesis (4/10 steps found)
- superpathway of demethylmenaquinol-6 biosynthesis I (3/9 steps found)
- superpathway of phylloquinol biosynthesis (7/15 steps found)
KEGG Metabolic Maps
- Alkaloid biosynthesis II
- Benzoate degradation via CoA ligation
- Biosynthesis of plant hormones
- Caprolactam degradation
- Ethylbenzene degradation
- Geraniol degradation
- Limonene and pinene degradation
- Propanoate metabolism
- Tyrosine metabolism
- Ubiquinone and menaquinone biosynthesis
- alpha-Linolenic acid metabolism
Isozymes
Compare fitness of predicted isozymes for: 6.2.1.-, 6.2.1.26
Use Curated BLAST to search for 6.2.1.- or 6.2.1.26
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (525 amino acids)
>TX73_009065 fatty acid--CoA ligase (Rhodopseudomonas palustris CGA009) MSEATEPATLADVIRAQANTRGNEIAYEFEGRISTFADFDRHTNQVARALQASGVQPNER IAYLGKNSDIYFELWSGAIKAKAVMAPVNWRLAGPEIAYIVEDCKAAILFVGPEFVDQVC GLKDQIPSVRHIITTEGGAPEWQDFTKWRDAQSSDDPQVAIAPSDIAIQLYTSGTTGKPK GAMLSHANFLSLVRAGQDNKPEWNRWSPDDVSLVAMPVFHIGGSGWGMMGIYHGAKGVIA REFDPTKVLDFFEQSGITKLFMVPAAMQFVVRQPRAREVDFSRLKYMLYGASPIPAALLK ECIDVFKCGFVQMYGMTETTGTIVALPPEDHVEGLERMRSAGKALPGVEIAILDPDGKPL PPRQVGEIATRSGSNMVGYWNLPDATKKTIDGDNWLRTGDAGYMDEDGYVYIHDRIKDMI ISGGENIYPAEVESAICDHPDVAEVAVVGVPDDQWGESVKAVVVMKPGKEATAQDIIGFT RTRIAGYKTPKSIDFIPALPRNASGKILRRQLRDPYWSGKDRQVN