Protein Info for TX73_009060 in Rhodopseudomonas palustris CGA009

Annotation: acyl-CoA dehydrogenase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02770: Acyl-CoA_dh_M
  • amino acids 151 to 249 (99 residues), 78.9 bits, E=5.1e-26
• PF00441: Acyl-CoA_dh_1
  • amino acids 261 to 412 (152 residues), 128.7 bits, E=4.4e-41
• PF08028: Acyl-CoA_dh_2
  • amino acids 278 to 392 (115 residues), 47.3 bits, E=5e-16

Best Hits

KEGG orthology group: K00249, acyl-CoA dehydrogenase [EC: 1.3.99.3] (inferred from 100% identity to rpa:RPA1762)

Predicted SEED Role

"Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)" in subsystem Isoleucine degradation (EC 1.3.99.2)

MetaCyc Pathways

• 1-butanol autotrophic biosynthesis (engineered) (21/27 steps found)
• pyruvate fermentation to butanol II (engineered) (4/6 steps found)
• pyruvate fermentation to hexanol (engineered) (7/11 steps found)

KEGG Metabolic Maps

• Butanoate metabolism
• Fatty acid metabolism
• Propanoate metabolism
• Valine, leucine and isoleucine degradation
• beta-Alanine metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.2, 1.3.99.3

Use Curated BLAST to search for 1.3.99.2 or 1.3.99.3

Protein Sequence (424 amino acids)

>TX73_009060 acyl-CoA dehydrogenase family protein (Rhodopseudomonas palustris CGA009)
MDFSLPPDLVAYLAELDRFIESKIKPLEQADDNIRFFDHRREWARTDFEHGGLPRHEWED
LLRKAKNLADDAGHLRFAIPKRYGGQDGTNLWMAVIREHFAAKGLGLHNDLQNEHSIVGN
FPIVKMLDLYGSPEQKAMIDGSITGKYRITFGLTEPDHGSDATHMETRAEEAVRDGKKGW
VINGEKMWTTGMHVATHCALFARTAGKDGDARGITCFLVPADAPGVKVEEYLWTFNMPTD
HPRVSFKDVFVTEDAVFGEVGRGLSLAQCFVHENRIRQAASSLGAAVFCINESVKYARER
KPFGEELARNQAIQFPLVELATQAEMLRLLIRKTAWEMDQMTQAQVEHTLSDKVSMCNYW
ANRLCGQAADRAIQVHGGIGYSRHKQFEHIYRHHRRYRITEGSEEIQMRKVAGFLFGYMG
ANKR