Protein Info for TX73_008190 in Rhodopseudomonas palustris CGA009

Annotation: toll/interleukin-1 receptor domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 316 PF13676: TIR_2" amino acids 4 to 113 (110 residues), 57.9 bits, see alignment E=1.6e-19 PF01582: TIR" amino acids 8 to 100 (93 residues), 24 bits, see alignment E=3.1e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to rpt:Rpal_1783)

Predicted SEED Role

"Chaperone protein DnaK" in subsystem Heat shock dnaK gene cluster extended or Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (316 amino acids)

>TX73_008190 toll/interleukin-1 receptor domain-containing protein (Rhodopseudomonas palustris CGA009)
MPKVFFSYSHADEALRDQIETQLALLKRQGIIDVWHDRRIGAGREFAREIDQHVESDEII
LLLVSADFLASDYCYEKEMLRALTRHDAGEAVVIPVILRACDWHGAPFGKLNAVPRDGKP
ITQFADRDAAMLEVARAVRSVAERFGSVASPKKTAQDVARSSLQGALSPRSSNLRLAKTF
NDKDKDEFRTEGFEYLSRFFENSIAELSKRNPGIEATFRKIDANRFVAKAYRNGRSATSC
TVFMGGMMGNGISYLARETTESNSHNEMLTVEADDQALYFQSFGMAVGRGNRQKLSYEGA
AELYWTMFIEPLQQGK