Protein Info for TX73_008140 in Rhodopseudomonas palustris CGA009

Annotation: hemolysin III family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 231 transmembrane" amino acids 35 to 58 (24 residues), see Phobius details amino acids 65 to 87 (23 residues), see Phobius details amino acids 99 to 117 (19 residues), see Phobius details amino acids 123 to 144 (22 residues), see Phobius details amino acids 153 to 172 (20 residues), see Phobius details amino acids 180 to 200 (21 residues), see Phobius details amino acids 208 to 229 (22 residues), see Phobius details PF03006: HlyIII" amino acids 34 to 222 (189 residues), 103 bits, see alignment E=1e-33

Best Hits

Swiss-Prot: 36% identical to YQFA_SHIFL: UPF0073 inner membrane protein YqfA (yqfA) from Shigella flexneri

KEGG orthology group: K11068, hemolysin III (inferred from 100% identity to rpt:Rpal_1773)

Predicted SEED Role

"COG1272: Predicted membrane protein hemolysin III homolog"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (231 amino acids)

>TX73_008140 hemolysin III family protein (Rhodopseudomonas palustris CGA009)
MTIFRLKQIVSHARIDAKGAVHWNYDRAELIADGVVHVLGLVAGLIAATALVTLTGVFAS
TPTIVSVSVYVAGLLAMLGLSAAYNLWPVSPRKWLLRRFDHSAIYILIAATYTPIISQIK
DQVFGLALLAGVWGVAVVGIVLKLFKPGKFDKLSVGLYLALGWSGIIAYDQVVETLPTTA
MWFLAIGGLLYTLGVIFHAWRRLRFQNAIWHAFVLVAAGCHYVAVMDLVLA