Protein Info for TX73_008010 in Rhodopseudomonas palustris CGA009

Annotation: form I ribulose bisphosphate carboxylase large subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 485 transmembrane" amino acids 261 to 280 (20 residues), see Phobius details PF02788: RuBisCO_large_N" amino acids 25 to 145 (121 residues), 156.9 bits, see alignment E=2.6e-50 PF00016: RuBisCO_large" amino acids 155 to 462 (308 residues), 437.1 bits, see alignment E=3.1e-135

Best Hits

Swiss-Prot: 100% identical to RBL1_RHOPA: Ribulose bisphosphate carboxylase large chain (cbbL) from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)

KEGG orthology group: K01601, ribulose-bisphosphate carboxylase large chain [EC: 4.1.1.39] (inferred from 100% identity to rpa:RPA1559)

MetaCyc: 60% identical to ribulose-bisphosphate carboxylase/oxygenase large subunit (Arabidopsis thaliana col)
Ribulose-bisphosphate carboxylase. [EC: 4.1.1.39]; 1.13.11.- [EC: 4.1.1.39]

Predicted SEED Role

"Ribulose bisphosphate carboxylase large chain (EC 4.1.1.39)" in subsystem CO2 uptake, carboxysome or Calvin-Benson cycle or Carboxysome or Photorespiration (oxidative C2 cycle) (EC 4.1.1.39)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.1.1.39

Use Curated BLAST to search for 4.1.1.39

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (485 amino acids)

>TX73_008010 form I ribulose bisphosphate carboxylase large subunit (Rhodopseudomonas palustris CGA009)
MNEAVTIRGKERYKSGVMEYKKMGYWEPDYEPKDTDVIALFRVTPQDGVDPIEAAAAVAG
ESSTATWTVVWTDRLTAAEKYRAKCYRVDPVPNSLGQYFAYIAYDLDLFEPGSISNLTAS
IIGNVFGFKPLKALRLEDMRLPIAYVKTFQGPATGIVVERERMDKFGRPLLGATVKPKLG
LSGRNYGRVVYEALKGGLDFTKDDENINSQPFMHWRERFQYCMEAVNKAQAQTGEIKGTY
LNVTAATMEDMYERAEYAKELGSIIVMIDLVIGYTAIQSMAKWARKNDMILHLHRAGHST
YTRQRNHGVSFRVIAKWMRLAGVDHIHAGTVVGKLEGDPATTKGYYDICREDFNPMTLEN
GLFFDQHWASLNKLMPVASGGIHAGQMHQLLHLLGEDVVLQFGGGTIGHPMGIAAGATAN
RVALEAMILARNEGRDYLHEGPEILAKAAQTCTPLKAALDTWKNVTFNYESTDTPDYAPT
PSVSV