Protein Info for TX73_006295 in Rhodopseudomonas palustris CGA009

Annotation: 2-oxoacid:acceptor oxidoreductase subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01855: POR_N
  • amino acids 26 to 257 (232 residues), 229.1 bits, E=6.2e-72
• PF17147: PFOR_II
  • amino acids 284 to 373 (90 residues), 78 bits, E=6.1e-26

Best Hits

Swiss-Prot: 48% identical to KORA_METTM: 2-oxoglutarate synthase subunit KorA (korA) from Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg)

KEGG orthology group: K00174, 2-oxoglutarate ferredoxin oxidoreductase subunit alpha [EC: 1.2.7.3] (inferred from 100% identity to rpt:Rpal_1419)

Predicted SEED Role

"2-oxoglutarate oxidoreductase, alpha subunit (EC 1.2.7.3)" (EC 1.2.7.3)

MetaCyc Pathways

• TCA cycle V (2-oxoglutarate synthase) (9/9 steps found)
• TCA cycle VII (acetate-producers) (9/9 steps found)
• TCA cycle VI (Helicobacter) (8/9 steps found)
• reductive TCA cycle I (7/11 steps found)
• incomplete reductive TCA cycle (4/7 steps found)
• reductive TCA cycle II (7/12 steps found)
• Methanobacterium thermoautotrophicum biosynthetic metabolism (19/56 steps found)

KEGG Metabolic Maps

• Citrate cycle (TCA cycle)
• Reductive carboxylate cycle (CO2 fixation)

Isozymes

Compare fitness of predicted isozymes for: 1.2.7.3

Use Curated BLAST to search for 1.2.7.3

Protein Sequence (387 amino acids)

>TX73_006295 2-oxoacid:acceptor oxidoreductase subunit alpha (Rhodopseudomonas palustris CGA009)
MNAPDRHVPKAAAAKLLSGNAACAQGAIDAGCKFFAGYPITPSSEIAERLSTMLPAAGGV
FIQMEDEIAAMAAVVGASMGGVKSLTATSGPGFSLKQENIGYAAGAEIPCVIVNVMRGGP
STGMPTRPSQADIFQTRYGSHGDYPMIVLAPASAREIYDETIRAFDLAELCRTPVILLYD
QVIAQSSETVTLGGRTSVHATRKWASGPREAYKPYAADADLVPPMPRPGDGYRTHTTGLT
HSETGFPSQDPETVTRNLGRLYGKLDRHRDLIDSYEAVRCEDVEVVIVAIGISARAARRA
VDACRAEGKKVGLFRPVTLWPFPEIALREATKNAKAILVPELNIGQLRLEIERQLRDRRV
EGLHLISGEPITPAQIAAAATKLASEV