Protein Info for TX73_005700 in Rhodopseudomonas palustris CGA009

Annotation: RNA polymerase sigma factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 422 TIGR02937: RNA polymerase sigma factor, sigma-70 family" amino acids 8 to 167 (160 residues), 56.2 bits, see alignment E=1.6e-19 PF04542: Sigma70_r2" amino acids 12 to 76 (65 residues), 45.7 bits, see alignment E=9.4e-16 PF08281: Sigma70_r4_2" amino acids 114 to 164 (51 residues), 40.9 bits, see alignment 2.6e-14 PF20239: DUF6596" amino acids 183 to 284 (102 residues), 121 bits, see alignment E=4.9e-39

Best Hits

Swiss-Prot: 71% identical to Y370_RHIME: Uncharacterized protein R00370 (R00370) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K03088, RNA polymerase sigma-70 factor, ECF subfamily (inferred from 100% identity to rpa:RPA1109)

Predicted SEED Role

"RNA polymerase sigma-70 factor, ECF subfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (422 amino acids)

>TX73_005700 RNA polymerase sigma factor (Rhodopseudomonas palustris CGA009)
MTDLAWIETAITAARPQAIGALLRYFRDLDTAEEAFQNACLRALKAWPENGPPRDPTAWL
IMIGRNVAIDDLRRGKKQQPLPDDAVISDLDDAEDALAERLDGSHYRDDILRLLFICCHP
ELPPTQQIALALRIVSGLTVPQIARAFLVSDAAMEQRITRAKAKVARAGMLFETPGAVER
AERLGAVAAMIYLLFNEGYSAAGETAGVRAPLCEEAIRLARLLLRLFPSEPEIMGLTALM
LLQHARAPARFDSGGTIVLLEDQDRSLWNATMIAEGLALIDKAMRHRRTGAYQIQAAIAA
LHARAPRYEDTDWAQIDLLYGSLEILQPSPVITLNRAVAVAKLRGPEAALAMIAPLEARL
GSYFHYFGAKGALLLQQGRCDEARTAFNRAIALARTPAEVSHIRMHLDRLMREADAAGRA
SA