Protein Info for TX73_005660 in Rhodopseudomonas palustris CGA009

Annotation: cytidine deaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00383: dCMP_cyt_deam_1
  • amino acids 7 to 108 (102 residues), 35 bits, E=5.4e-13

Best Hits

Swiss-Prot: 47% identical to BSR_BACCE: Blasticidin-S deaminase (bsr) from Bacillus cereus

KEGG orthology group: K01489, cytidine deaminase [EC: 3.5.4.5] (inferred from 100% identity to rpa:RPA1101)

Predicted SEED Role

"Cytidine deaminase (EC 3.5.4.5)" in subsystem Murein hydrolase regulation and cell death (EC 3.5.4.5)

MetaCyc Pathways

• pyrimidine deoxyribonucleosides degradation (2/3 steps found)
• pyrimidine ribonucleosides degradation (1/2 steps found)
• pyrimidine ribonucleosides salvage II (1/2 steps found)
• superpathway of pyrimidine deoxyribonucleoside salvage (6/9 steps found)
• pyrimidine ribonucleosides salvage I (1/3 steps found)
• superpathway of pyrimidine ribonucleosides salvage (6/10 steps found)
• pyrimidine deoxyribonucleosides salvage (2/5 steps found)
• superpathway of pyrimidine ribonucleosides degradation (2/5 steps found)
• superpathway of pyrimidine deoxyribonucleosides degradation (2/6 steps found)

KEGG Metabolic Maps

• Drug metabolism - other enzymes
• Pyrimidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.4.5

Protein Sequence (141 amino acids)

>TX73_005660 cytidine deaminase (Rhodopseudomonas palustris CGA009)
MSITDADRALIDAAIEAITRRYRNDWQEVGAALLTRTGKRYVAVNLDAYLGRMAVCAEAV
ALGQVITELGDAGIDTIVAVRHPKPHEADREVRVVSPCGACRELIWDYDRNARVLVPGPD
GIEAVGISELLPNKYSRERVL