Protein Info for TX73_005015 in Rhodopseudomonas palustris CGA009
Annotation: hydrogenase nickel incorporation protein HypB
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 66% identical to HYPB_RHILV: Hydrogenase maturation factor HypB (hypB) from Rhizobium leguminosarum bv. viciae
KEGG orthology group: K04652, hydrogenase nickel incorporation protein HypB (inferred from 100% identity to rpt:Rpal_1166)Predicted SEED Role
"[NiFe] hydrogenase nickel incorporation-associated protein HypB" in subsystem NiFe hydrogenase maturation
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (318 amino acids)
>TX73_005015 hydrogenase nickel incorporation protein HypB (Rhodopseudomonas palustris CGA009) MCTVCGCGDASADPGHGHDHPHSHGHSHGDGHAHHHHHHHDHDHAHPHTHDHDHGHDHHH DHGHDHGHVHAPAGGSIDFGAGLAGVHIPGLSQPRIVQIERDILSKNDAYAAENRARLAA SGTFALNFVSSPGSGKTSLLVKTISDLKDQYPIAVVEGDQQTANDAERIRATGAPAIQIN TGKGCHLDAHMVGHALDQLPRHEGGLLFIENVGNLVCPAGFDLGEAHKVVVLSITEGEDK PLKYPHMFAAAKLLLLNKIDLLPHLDFDLAATIEYARRVNPTIEVLTVSAKTGEGLAAFY AWIGKRAAAVRAAANAAE