Protein Info for TX73_004890 in Rhodopseudomonas palustris CGA009

Annotation: MATE family efflux transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 474 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 36 to 48 (13 residues), see Phobius details amino acids 64 to 91 (28 residues), see Phobius details amino acids 111 to 130 (20 residues), see Phobius details amino acids 150 to 171 (22 residues), see Phobius details amino acids 180 to 199 (20 residues), see Phobius details amino acids 211 to 236 (26 residues), see Phobius details amino acids 258 to 284 (27 residues), see Phobius details amino acids 296 to 316 (21 residues), see Phobius details amino acids 335 to 355 (21 residues), see Phobius details amino acids 375 to 398 (24 residues), see Phobius details amino acids 410 to 433 (24 residues), see Phobius details amino acids 439 to 458 (20 residues), see Phobius details PF01554: MatE" amino acids 38 to 197 (160 residues), 89.9 bits, see alignment E=7.4e-30 amino acids 264 to 429 (166 residues), 100.4 bits, see alignment E=4.5e-33 TIGR00797: MATE efflux family protein" amino acids 38 to 442 (405 residues), 258.4 bits, see alignment E=5.4e-81

Best Hits

Swiss-Prot: 100% identical to NORM_RHOPA: Probable multidrug resistance protein NorM (norM) from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)

KEGG orthology group: K03327, multidrug resistance protein, MATE family (inferred from 100% identity to rpt:Rpal_1019)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (474 amino acids)

>TX73_004890 MATE family efflux transporter (Rhodopseudomonas palustris CGA009)
MVRAMTAPGSNIAAGALAPAKSSAWRTELIETLWLAWPMALTQLGQIAMMTTDLALIGRL
GDAAVAAAALAHFVLFSTFTMGLGLVSAVTPLAAQAFGARAPRQVRASLRVGLWAGVIAG
VPLTLGQLYGEELLVALGQNPATSRLAGDYLDGLAWSLVPGWLFIALRGLMGAVNRPEPA
LWIMLTAIPINLGLAYVLIHGSFGLPRLEIFGAGLATSIVSWAMCIAAAVVCVTMRPFRK
YQVFGELFRFDGELMRRLLQLGLPISGASVLEYGVFGAAALLMGKFGTTALAAHQIALQV
AAIMFMVPMGISVAATVRVGHAVGRGDPPSARRAGFAAIGLGFVFMAAMTLLVALTRHQI
PQLFLGDSDTSIETATLTAALLIVGASFFIADGLQVVANGALRGRNDTKVPLLFAVLGFW
VIGFPFCWVLGFHTDLGPFGVWIGLAVGLVVYAALLVWRFHRLTRDAMAAAVAA