Protein Info for TX73_004765 in Rhodopseudomonas palustris CGA009

Annotation: cyclopropane-fatty-acyl-phospholipid synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 341 PF02353: CMAS" amino acids 63 to 297 (235 residues), 137.9 bits, see alignment E=1.7e-43 PF13489: Methyltransf_23" amino acids 102 to 231 (130 residues), 53 bits, see alignment E=1.4e-17 PF05175: MTS" amino acids 107 to 189 (83 residues), 29.8 bits, see alignment E=1.8e-10 PF13847: Methyltransf_31" amino acids 115 to 222 (108 residues), 40.2 bits, see alignment E=1.2e-13 PF02390: Methyltransf_4" amino acids 119 to 176 (58 residues), 26.2 bits, see alignment E=2e-09 PF13649: Methyltransf_25" amino acids 120 to 214 (95 residues), 57.6 bits, see alignment E=6.6e-19 PF08241: Methyltransf_11" amino acids 121 to 217 (97 residues), 51.4 bits, see alignment E=5.5e-17 PF08242: Methyltransf_12" amino acids 121 to 216 (96 residues), 41.9 bits, see alignment E=5.4e-14

Best Hits

Swiss-Prot: 34% identical to CNMT_THLFG: (S)-coclaurine N-methyltransferase from Thalictrum flavum subsp. glaucum

KEGG orthology group: None (inferred from 100% identity to rpa:RPA0924)

MetaCyc: 42% identical to phenylalkylamine N-methyltransferase (Ephedra sinica)
2.1.1.M76 [EC: 2.1.1.M76]; 2.1.1.M76 [EC: 2.1.1.M76]; 2.1.1.M76 [EC: 2.1.1.M76]; 2.1.1.M76 [EC: 2.1.1.M76]; 2.1.1.M76 [EC: 2.1.1.M76]

Predicted SEED Role

"Cyclopropane-fatty-acyl-phospholipid synthase-like protein, clusters with FIG005069"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.M76

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (341 amino acids)

>TX73_004765 cyclopropane-fatty-acyl-phospholipid synthase (Rhodopseudomonas palustris CGA009)
MSGLASLIDIAERVPLPDAVIRAGIRMLCARTAAKMALGNAASDAAFAQAMAAREVAEHP
DAANAQHYEVPAEFFGKVLGPHRKYSSCFYREAETTLAQAEAEALRLTMEHADLRDGQAI
LELGCGWGSLSLAMAERFPYARILSVSNSASQRQYIEAQAAARRLMNLRVVTCDMNAFEP
HDKFDRVVSVEMFEHMMNWRKLMTWIRGWLKPGGLFFMHIFSHRRGAYLFDRTDRADWIA
QHFFTGGVMPSHRLILQYADLFKIDEQWRWSGRHYRRTAEDWLVNFDKHRDEIEAILRPV
YGDDTALWMRRWRWFFLATSGLFGYADGDEWGVSHYRLKPA