Protein Info for TX73_004715 in Rhodopseudomonas palustris CGA009

Annotation: EAL domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 959 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 182 to 203 (22 residues), see Phobius details amino acids 210 to 231 (22 residues), see Phobius details amino acids 246 to 267 (22 residues), see Phobius details amino acids 277 to 295 (19 residues), see Phobius details amino acids 301 to 322 (22 residues), see Phobius details amino acids 330 to 352 (23 residues), see Phobius details amino acids 358 to 378 (21 residues), see Phobius details PF00989: PAS" amino acids 405 to 511 (107 residues), 39.3 bits, see alignment E=2.1e-13 TIGR00229: PAS domain S-box protein" amino acids 406 to 520 (115 residues), 47.3 bits, see alignment E=2.2e-16 PF08447: PAS_3" amino acids 420 to 507 (88 residues), 61.2 bits, see alignment E=3.4e-20 PF08448: PAS_4" amino acids 421 to 513 (93 residues), 29.8 bits, see alignment E=2.1e-10 PF13426: PAS_9" amino acids 421 to 513 (93 residues), 31.5 bits, see alignment E=6.1e-11 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 524 to 686 (163 residues), 101.1 bits, see alignment E=5.3e-33 PF00990: GGDEF" amino acids 526 to 682 (157 residues), 120 bits, see alignment E=3.1e-38 PF00563: EAL" amino acids 703 to 939 (237 residues), 230.5 bits, see alignment E=6.6e-72

Best Hits

KEGG orthology group: None (inferred from 92% identity to bja:bll1502)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (959 amino acids)

>TX73_004715 EAL domain-containing protein (Rhodopseudomonas palustris CGA009)
MRLIRCLALLALGVMLVAAAPQAHALDAVSVRSDAPAIDLTGVLEHLHSDNDRVQISTAP
GNDGIVRRVEVRAREGGQNWVVFALANNSDDQLDRLIVAPHYRMVGSGLLWPDLGMSRIA
TITPSTGDRPERQDSATADIFRVTLDPGSVITFVAELRTDKLPQLYLWEPEAYKDKVNSF
TLYQGIVIGISGLLALVLTILFVVKGSIMFPAAAALAWAVLVYIGIDFGFWGKVLDMSSG
AERVWRASGEAILAATLLVFLFAYLNLSRWHVRYSHITLGWLAFLGSLVALALFDPAVAS
GIARISLVAIAFAGFALIVYLSTHGFDRAVLLIPTWFLLVVWVVASGMAVAGTVTNDIVG
PALLGGLVLIVMLIGFTVMQHAFSGGGATGGVISDVERRALALIGSGDLIWDWDVSADKV
FTSPETEALLGLKRGALEGSAASWLEVLHPLDQDRFRAALDSVLDQRRGRLTQDFRLRTP
DGHFMWFSLKARPVVGTDGEVTRVVGTLTDVTEIKNAEERMLHDSVHDNLTGLPNRKLFI
DRLGAVSNFAKTMPTLRPTLMVIDLDRFKQVNDSVGIAVGDSILLTLARRLSRILKPQDT
LARIAGDQFGLILLSEQDPAKITAFAETIRKTIKAPIAFNDREIFLTASIGLALSDPQTQ
LSDEIIKDAELAMYHSKRIGGDRIDVYKPAMRARKSDRLTLESELRRAIERKEITILYQP
IVRLEDRSIAGFEALARWDHPKLGRMSPSEFISIAEEIGLIVELGTFVLDQTAKQLSIWQ
RAMRAREPIFASVNVSSRQLLRHDLLHDIRTVTSRSSVARGTLKLELTESLVMENPEHAA
QMLQRIRELGVGLALDDFGTGHSSLSYLQRFPFDTIKIDQSFVRTTSRGTRPVILKSIIA
LAHDLGMDVVAEGAETDSDAVELYQLGCEYAQGFAFGEPMDVDAAMKLLTEEQRLEAAS