Protein Info for TX73_004565 in Rhodopseudomonas palustris CGA009

Annotation: diguanylate cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 502 transmembrane" amino acids 21 to 45 (25 residues), see Phobius details amino acids 296 to 317 (22 residues), see Phobius details PF02743: dCache_1" amino acids 52 to 238 (187 residues), 65.3 bits, see alignment E=6e-22 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 330 to 492 (163 residues), 158.4 bits, see alignment E=6.9e-51 PF00990: GGDEF" amino acids 334 to 489 (156 residues), 153.9 bits, see alignment E=3.3e-49

Best Hits

KEGG orthology group: None (inferred from 100% identity to rpt:Rpal_0954)

Predicted SEED Role

"InterPro IPR000160 COGs COG3706"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (502 amino acids)

>TX73_004565 diguanylate cyclase (Rhodopseudomonas palustris CGA009)
MDTHGLFNKISKELHRRRRMSARVMVAFSLVTVLGFSAVCGSVLLDMRRGAEELARQTLE
NLAASMDADINRNVELYDASLRAVASNLVLPELSQVDAKLARLILFDHPVTGPHFGAIRV
YDEHGNLTGDSALTNPQKENRASEPFFTVQRDEPYVGLYISKPQQVDGHYSVILSRRVTG
SDGRFLGVVAGSIKFDYFQDLFKRLRLRPQDMIAVIAHDGTLIVRTPFEPELIGKNMLVT
SGVQKMFGRRNGWFAGTGTLDGVKRMFVWSDSTKPLVVLVAKSWNDIYAMWRKEATWIGI
VLLALAAFVAAVTVFFIREIERRAAAERRLEELATTDPLTGLTNRRKFDAAIDTEWRRAI
RQNTPIALLMIDADHFKAYNDSFGHQAGDQMLVGIAVCIADTVHRAGDCVARFGGEEFAV
LLPGLTAPAAEAIAETIRRKVEEWSDIEGGVTVSIGVASTTPIAAHQWYDLVEAADRALY
AAKELGRNRCVVAVRGEVTLVA