Protein Info for TX73_004495 in Rhodopseudomonas palustris CGA009

Annotation: M3 family metallopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 696 PF01432: Peptidase_M3" amino acids 240 to 688 (449 residues), 425.2 bits, see alignment E=2.4e-131

Best Hits

KEGG orthology group: K01284, peptidyl-dipeptidase Dcp [EC: 3.4.15.5] (inferred from 100% identity to rpa:RPA0872)

Predicted SEED Role

"Dipeptidyl carboxypeptidase Dcp (EC 3.4.15.5)" in subsystem Protein degradation (EC 3.4.15.5)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.15.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (696 amino acids)

>TX73_004495 M3 family metallopeptidase (Rhodopseudomonas palustris CGA009)
MSESSGPIAAPADAGNPLLAAWTTPFETPPFAEIRPEHFMPAFEQAFADHAGEIAAIVND
PTEPDFDNTVTALERSGKLLNRVAAVFYDLVSAHSSPELLKIDEEVSLRMARHWNPIMMN
AVLFGRIAALRDKAARLNLTPEQSRLLERSYTRFHRAGAGLDEASKARMAAINERLAQLG
TSFSHHLLGDEQEWMMELGEGDTEGLPDSFVAAARAAAEERGLPGKAVVTLSRSSVEPFL
KMSSRRDLREKVYRAFIARGDNGNDNDNNAIIGEILSLREESAKLLGYPTFAAYRLEDSM
AKTPEAVRGLLERVWKPARARALADRDALQELVTEEGSNFKLAPWDWRYYAERLRQRRAN
FDDAAIKPYLTLDGMIAAAFDTATRLFGITFEERKDVPVWHPDVRVWEVKDADGAHRGLF
YGDYYARPSKRSGAWMTSLRDQQKLDSAVAPLIINVCNFAKGAGGEPSLLSPDDARTLFH
EFGHGLHGMLSDVTYPSLSGTSVFTDFVELPSQLYEHWQEQPQVLRQFARHYQTGEPLPD
DLLQRFIAARKFGQGFATVEFVSSALLDLEFHTQPAASIGEVRAFERKELDKIGMPEEIA
LRHRPTQFGHIFSGDHYASGYYSYMWSEVMDADAFGAFEEAGDIFAPDVAKRLRDDIYSS
GGSRDPEEAYVAFRGRKPEPDALLRRRGLLDTPEAA