Protein Info for TX73_004285 in Rhodopseudomonas palustris CGA009

Annotation: cytochrome c oxidase subunit II

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 285 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details transmembrane" amino acids 54 to 80 (27 residues), see Phobius details amino acids 101 to 123 (23 residues), see Phobius details PF02790: COX2_TM" amino acids 35 to 121 (87 residues), 87 bits, see alignment E=8e-29 TIGR02866: cytochrome c oxidase, subunit II" amino acids 45 to 263 (219 residues), 204.3 bits, see alignment E=7.2e-65 PF00116: COX2" amino acids 133 to 254 (122 residues), 154.6 bits, see alignment E=1e-49

Best Hits

Swiss-Prot: 50% identical to COX2_RICBR: Probable cytochrome c oxidase subunit 2 (ctaC) from Rickettsia bellii (strain RML369-C)

KEGG orthology group: K02275, cytochrome c oxidase subunit II [EC: 1.9.3.1] (inferred from 100% identity to rpt:Rpal_0899)

Predicted SEED Role

"Cytochrome c oxidase polypeptide II (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (285 amino acids)

>TX73_004285 cytochrome c oxidase subunit II (Rhodopseudomonas palustris CGA009)
MKVSKERLGRWSLGLAIACCAAAVGGTAFAEMGQPAPWEVTLQQPASPVMQNIVWFHSFL
LWLITLITLFVLALLVIVVVKFNAKANPVPSKTTHNTLIEVAWTIVPVLILVAVAVPSFR
LLFLELDIPKPDLTVKATGNQWNWTYTYPDDKIEFTSIMLTDEERAKMNPVPPRLLGVDN
EMVVPVDKVVRIQTTAADVIHSWAIPSFGVKIDAIPGRLNEAWFKAVKEGRYYGQCSELC
GRDHAFMPIVVRVVNEQEYEAWKKKQQVASRMRDDSYASAASATR