Protein Info for TX73_003790 in Rhodopseudomonas palustris CGA009

Annotation: NADH-quinone oxidoreductase subunit NuoF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01512: Complex1_51K
  • amino acids 145 to 315 (171 residues), 161.1 bits, E=2e-51
• PF10589: NADH_4Fe-4S
  • amino acids 427 to 507 (81 residues), 98.5 bits, E=1.7e-32

Best Hits

KEGG orthology group: K00124, formate dehydrogenase, beta subunit [EC: 1.2.1.2] (inferred from 100% identity to rpa:RPA0733)

Predicted SEED Role

"NAD-dependent formate dehydrogenase beta subunit" in subsystem Formate hydrogenase

KEGG Metabolic Maps

• Glyoxylate and dicarboxylate metabolism
• Methane metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.2.1.2

Use Curated BLAST to search for 1.2.1.2

Protein Sequence (518 amino acids)

>TX73_003790 NADH-quinone oxidoreductase subunit NuoF (Rhodopseudomonas palustris CGA009)
MSLRIFIPRDSGALAVGADEVAAALVDQAHARELPVDLVRPGSRGLYWLEPMLEVDTPEG
RVAYGPVTPADVPSLLDAIVAGGPHPLQQGLTEEIPWLKRQTRLTFARCGIVDPRSIDDY
RAHGGYRGLERALKMSSDAIIDDVVKSGLRGRGGAGFPTGTKWRTVAQAGRGQKYICCNA
DEGDSGTFADRMLMEGDPFMIIEGMTIAGIAVGATKGYIYIRSEYPHAVEAMNAAIEAAR
RTGYLGEHICHSTDSFDIEVRVGAGAYICGEETSMLESLEGKRGTVRAKPPLPAHKGLFG
RPTVINNVLTFSAVPYILDGGAQAYADCGMGKSRGTKPIQLGGNIKHGGLFEVAFGITLG
ELVDEIGGGTLSGRPVRAVQVGGPLGAYFPRALFDTPFDYEAFAARSGMVGHGGVVVFDD
TVDMAKQARFAMEFCAHESCGKCTPCRIGSTRGAETVDKIIAGDRPAANIAVLEDLCNTM
KFGSLCALGGLAPIPVLSALTHFPEDFGLAPRRLQAAE