Protein Info for TX73_003570 in Rhodopseudomonas palustris CGA009
Annotation: phosphonate C-P lyase system protein PhnL
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 56% identical to PHNL_ECOLI: Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL (phnL) from Escherichia coli (strain K12)
KEGG orthology group: K05780, putative phosphonate transport system ATP-binding protein (inferred from 98% identity to rpx:Rpdx1_0742)MetaCyc: 56% identical to ATP-binding cassette protein PhnL (Escherichia coli K-12 substr. MG1655)
Predicted SEED Role
"Phosphonates transport ATP-binding protein PhnL" in subsystem Alkylphosphonate utilization
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (236 amino acids)
>TX73_003570 phosphonate C-P lyase system protein PhnL (Rhodopseudomonas palustris CGA009) MTMTQAPALVVDNAQKSFVMHLQGGVTLPVVRGVSFQVQPGECVVLSGPSGAGKSSILKM IFGNYRCDSGAIRIAHEGDTLDIATAQPRQILAARRGSIGYVSQFLRAVPRVAALDVVAE PLIVQGTAREAASEQAGVLLRRLNIPERLWTLPPATFSGGEQQRVNIARGFISHTPILLL DEPTASLDAKNRAVVVELIGQTKAQGAAIIAIVHDDEIREIIADRIVDVTSFAAAA