Protein Info for TX73_003415 in Rhodopseudomonas palustris CGA009

Annotation: benzoyl-CoA reductase subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 437 TIGR02259: benzoyl-CoA reductase, subunit A" amino acids 1 to 431 (431 residues), 926.1 bits, see alignment E=2.7e-283 PF01869: BcrAD_BadFG" amino acids 5 to 431 (427 residues), 298.8 bits, see alignment E=2.1e-93 TIGR00241: putative CoA-substrate-specific enzyme activase" amino acids 222 to 427 (206 residues), 166.8 bits, see alignment E=6.5e-53

Best Hits

Swiss-Prot: 71% identical to BCRA_THAAR: Benzoyl-CoA reductase subunit A (bcrA) from Thauera aromatica

KEGG orthology group: K04114, benzoyl-CoA reductase subunit [EC: 1.3.7.8] (inferred from 100% identity to rpt:Rpal_0726)

MetaCyc: 100% identical to BadF (Rhodopseudomonas palustris)
1.3.99.15-RXN [EC: 1.3.7.8]

Predicted SEED Role

"Benzoyl-CoA reductase subunit BadF (EC 1.3.99.15)" (EC 1.3.99.15)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.7.8, 1.3.99.15

Use Curated BLAST to search for 1.3.7.8 or 1.3.99.15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (437 amino acids)

>TX73_003415 benzoyl-CoA reductase subunit A (Rhodopseudomonas palustris CGA009)
MRTFVGIDLGSTTTKAVLMDENKEVIGRGITNSRSNYATAARVASEEARIDARFTLFRRA
LHVGEAGHEHSAEFLAALERNFRLIQFLEQLDDLEETCHRQLEAERFKAVAGPLQEALHV
IFARLREEAASLYAPGAKRKSDFFRDIAGSRFHVHAEAVAREMGIALEMVLNAYDKSIIE
VENRPPGGELSEKFRRAVARMLAVDSHAADGEGDFAAMIESALGIELEETYLVGTGYGRV
TLPFSKEHIRSEILCHGLGAHMMYPGTRTVLDIGGQDTKGIQIDGHGIVENFQMNDRCAA
GCGRYLGYIADEMNMGLHELGPLAMQSSRPARINSTCTVFAGAELRDRLSLGEKREDILA
GLHRAIILRAISIISRSGGVTDQFTFTGGVAKNEAAVRELRKLIQENYGEVTININPDSI
YTGALGASEFARRAVAA