Protein Info for TX73_003220 in Rhodopseudomonas palustris CGA009

Annotation: methionyl-tRNA formyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 310 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details TIGR00460: methionyl-tRNA formyltransferase" amino acids 4 to 301 (298 residues), 257.6 bits, see alignment E=7.7e-81 PF00551: Formyl_trans_N" amino acids 4 to 181 (178 residues), 135.8 bits, see alignment E=1.5e-43 PF02911: Formyl_trans_C" amino acids 205 to 301 (97 residues), 83.6 bits, see alignment E=9.9e-28

Best Hits

Swiss-Prot: 100% identical to FMT_RHOPA: Methionyl-tRNA formyltransferase (fmt) from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)

KEGG orthology group: K00604, methionyl-tRNA formyltransferase [EC: 2.1.2.9] (inferred from 100% identity to rpa:RPA0622)

Predicted SEED Role

"Methionyl-tRNA formyltransferase (EC 2.1.2.9)" in subsystem Conserved gene cluster associated with Met-tRNA formyltransferase or Folate Biosynthesis (EC 2.1.2.9)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (310 amino acids)

>TX73_003220 methionyl-tRNA formyltransferase (Rhodopseudomonas palustris CGA009)
MPLRLVFMGTPEFAVPTLLALAAHGHDIAAVYTREPKPAGRGMKLQETAVALAAHRLQAP
VLTPKTLRTDEALANFRAHEADAAVVVAYGMILPQAILDAPELGCYNLHGSLLPRWRGAA
PLNRAIMAGDAETGVMVMKMDAGLDTGDVAMAERIAITDAMTVTDVHDQLARLGADLMVR
AMAALERGGLQLTKQSEDGVTYAAKIDKAEAKIDFAKPTRAVLRHIHGLSPFPGAWCELP
IEGQPVRIKVLRCAIADGRGEPGEVIDDHLTIACGDGAIRVSQLQRAGKQPMTAEEFLRG
TPIAKGVRVG