Protein Info for TX73_003130 in Rhodopseudomonas palustris CGA009

Annotation: phosphoenolpyruvate--protein phosphotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 755 transmembrane" amino acids 32 to 49 (18 residues), see Phobius details amino acids 688 to 701 (14 residues), see Phobius details PF01590: GAF" amino acids 26 to 157 (132 residues), 58.9 bits, see alignment E=2e-19 PF13185: GAF_2" amino acids 31 to 160 (130 residues), 41.1 bits, see alignment E=5.4e-14 PF05524: PEP-utilisers_N" amino acids 185 to 303 (119 residues), 81.5 bits, see alignment E=1.4e-26 TIGR01417: phosphoenolpyruvate-protein phosphotransferase" amino acids 185 to 733 (549 residues), 403.9 bits, see alignment E=5.1e-125 PF00391: PEP-utilizers" amino acids 330 to 403 (74 residues), 56.9 bits, see alignment E=3.5e-19 PF02896: PEP-utilizers_C" amino acids 429 to 715 (287 residues), 297.1 bits, see alignment E=3.3e-92

Best Hits

KEGG orthology group: K08484, phosphotransferase system, enzyme I, PtsP [EC: 2.7.3.9] (inferred from 100% identity to rpa:RPA0605)

Predicted SEED Role

No annotation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.3.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (755 amino acids)

>TX73_003130 phosphoenolpyruvate--protein phosphotransferase (Rhodopseudomonas palustris CGA009)
MRSTSGGPRVLLRRLRETMAEQVSAQERLDKIVVLIAANMVAEVCSVYVLRIDNTLELYA
TEGLNREAVHQTVLNAHEGLVGLVASEATPLNLSDAQSHPAFSFRPETGEEIYHSFLGVP
ILRAGNTLGVLVVQNRAKRTYVEEEVEALQTTAMVLAEMIASGELSALAQPGAEPAARHS
IHKTGAVLSDGIALGHVVLHEPRVVITNYIAEDLPKEIKRLDAALAKLRSDLDRMLERGD
FAEGGEHRDVLEAYRMFANDHGWSHKLHEAVATGLTAEAAVERVQSDTRARMLRSTDPYL
RDRLHDLEDLGHRLMRQLVGQDHAPSREQLPDNAILIARSMGPAALLDYDRKRLRGLVLE
EGTANSHVSIVARALGIAAIGEVPNAPGIADPGDAIIVDATSGSIYVRPSAEIEAAYAER
VRFRARRQAQYSALRDLPCATKDGQPIDLMINAGLTIDLPHIEDTGSSGIGLFRTELQFM
VGQSLPRSSDQLALYRAVLDAAGSKPVTFRTLDIGGDKALPYMETVVEENPALGWRAIRL
GLDRPGLLRSQIRALLRAAAGRYLRVMFPMISEVAEFDAAKSIIERELTYLRQHGHTLPE
RVDVGTMLEVPALLYQLDELFKRADFVSVGSNDLFQFLFAVDRGNSKVSERFDTLSAPIL
RALRDIVRKARAAKRSLSLCGEMASQPLAALALIAIGYRSLSVSALAHGPVKAMILGLDL
AKAEAMIGPLLDAPAGSVSIRDKLIEFAEAHQLAL