Protein Info for TX73_002770 in Rhodopseudomonas palustris CGA009

Annotation: ATP-dependent helicase HrpB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 825 TIGR01970: ATP-dependent helicase HrpB" amino acids 9 to 824 (816 residues), 1052 bits, see alignment E=0 PF00270: DEAD" amino acids 24 to 169 (146 residues), 34.5 bits, see alignment E=5.4e-12 PF00271: Helicase_C" amino acids 209 to 334 (126 residues), 45.9 bits, see alignment E=1.8e-15 PF04408: HA2_N" amino acids 396 to 419 (24 residues), 21.8 bits, see alignment (E = 4.9e-08) PF21010: HA2_C" amino acids 425 to 487 (63 residues), 24.8 bits, see alignment 7.9e-09 PF08482: HrpB_C" amino acids 679 to 811 (133 residues), 175 bits, see alignment E=3e-55

Best Hits

KEGG orthology group: K03579, ATP-dependent helicase HrpB [EC: 3.6.4.13] (inferred from 100% identity to rpa:RPA0535)

Predicted SEED Role

"ATP-dependent helicase HrpB"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (825 amino acids)

>TX73_002770 ATP-dependent helicase HrpB (Rhodopseudomonas palustris CGA009)
MTRTFDTPLPIDDALDELTAALEASNTAVLVAPPGAGKTTRVPLALLDAPWLRNQKIIVL
EPRRIAARASAERMAKTLSEKAGERIGYRVRFGSKVSRATRIEVVTEGIFTRQILDDPEL
NGVAAVLFDEFHERSLDADLGLALARDAQQGLREDLRILVMSATIDGARVARLLGDAPVV
ESLGRAFPVETRYLGRRSDAPLERQMAEAIAQALRAETGSVLAFLPGAAEIRRTETMLRE
RVQDPAVEIVPLFGALDAAVQDRAIQPAPKGQRKVVLATSIAETSLTIEGVRIVVDCGLS
RVPRYEPDLGLTRLETVRASRAAVDQRRGRAGRIEPGVCYRLWDEPQTASLPAYTQPEIL
SADLSSLLLDLAQWGVADPSSLAFLDPPPQPALKEARELLGELGALDPDGRITDEGRSLR
AMALPPRLARMIVDAARHDCAKDAAEVAAILTERGLGGDSADLDNRRDQFRRDRSQRASS
ARQMAQRWATQAASSSPSPQDAGELSSGVLLAFAFPDRVAKNRGNGSFTLANGRGAAVEQ
TSALARAPYLAVGELTGSAAQGRILLAAPIALSEIELHFGDQITDADEVSFDRSAMALRA
RRRRALHAITLSEAPLALTPSEQTARVLAEGLVVAGLDRLPWSKQLQQWRGRVMFLRKAE
GDPWPDLSDAALAETRENWLVPALFDKTGLKDFSASDLSDALMNLLPWELRARLDREAPT
HFEAPTGSKLPIDYEAEQGPTIAVRLQELFGLTTHPSVAGGAVPLVLELLSPAHRPVQVT
RDLPGFWRGSYAGVRADLRGRYPRHPWPEDPASAPPTRRAKPKGT