Protein Info for TX73_002665 in Rhodopseudomonas palustris CGA009

Annotation: DHA2 family efflux MFS transporter permease subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 520 transmembrane" amino acids 19 to 41 (23 residues), see Phobius details amino acids 55 to 76 (22 residues), see Phobius details amino acids 84 to 103 (20 residues), see Phobius details amino acids 109 to 131 (23 residues), see Phobius details amino acids 143 to 164 (22 residues), see Phobius details amino acids 170 to 191 (22 residues), see Phobius details amino acids 203 to 222 (20 residues), see Phobius details amino acids 234 to 251 (18 residues), see Phobius details amino acids 272 to 293 (22 residues), see Phobius details amino acids 304 to 326 (23 residues), see Phobius details amino acids 337 to 356 (20 residues), see Phobius details amino acids 366 to 389 (24 residues), see Phobius details amino acids 402 to 422 (21 residues), see Phobius details amino acids 481 to 499 (19 residues), see Phobius details TIGR00711: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family" amino acids 18 to 487 (470 residues), 388.1 bits, see alignment E=3.1e-120 PF00083: Sugar_tr" amino acids 19 to 195 (177 residues), 41.6 bits, see alignment E=7.8e-15 PF07690: MFS_1" amino acids 23 to 414 (392 residues), 190.6 bits, see alignment E=3.8e-60

Best Hits

KEGG orthology group: K03446, MFS transporter, DHA2 family, multidrug resistance protein B (inferred from 100% identity to rpa:RPA0514)

Predicted SEED Role

"drug resistance transporter, EmrB/QacA subfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (520 amino acids)

>TX73_002665 DHA2 family efflux MFS transporter permease subunit (Rhodopseudomonas palustris CGA009)
MAGAAQSHAVPGFRRNMVTICAMTATIMQALDTTIANVALPYMQGSLSASQDQINWVLTS
YIVAAAIMTAPVGWIANRFGRKRIFIICSAGFTIASVMCGLAQDITQMVVFRLLQGVFGA
ALVPLSQAVMLDSYALHERAKAMSIWGMGVMMGPIMGPSLGAWLTETYSWHWVFFVNLPF
GAITVLGLAMFMDETDKNQELKFDWFGFAALAVGIGAMQLALDRGEQLDWFNSPEIIIES
IVSVVGFYYFFAHSFTTERPFIQFAIFKDRNFVGGVVFMTVMGLVLFSTMALSSPFLQNV
EGYPIMTAGLLLASRGCGTFVAMMIVGRIMRYIEARTLIATGLSLTCASLYVMTGWTDQT
SVSSVVVTSIIQGFGFGLVFVPLSTVAFMTLPGQLRTDGTAMLTLVRNVASSVGISVVIA
KLSSGTTTAHAILTEHINPFNNALQMPNVTGMIDLSTTTGKAMMDAIVTMQAQIIAFSHD
YAMVMFLTAAAVPMAIIIGSTKAALRKQSEAPADHAAVME