Protein Info for TX73_002460 in Rhodopseudomonas palustris CGA009

Annotation: NADP-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 333 transmembrane" amino acids 121 to 137 (17 residues), see Phobius details PF16884: ADH_N_2" amino acids 7 to 112 (106 residues), 99.6 bits, see alignment E=1.4e-32 PF00107: ADH_zinc_N" amino acids 158 to 283 (126 residues), 66.4 bits, see alignment E=3.7e-22 PF13602: ADH_zinc_N_2" amino acids 190 to 328 (139 residues), 43.4 bits, see alignment E=1e-14

Best Hits

Swiss-Prot: 47% identical to PTGR1_RAT: Prostaglandin reductase 1 (Ptgr1) from Rattus norvegicus

KEGG orthology group: K07119, (no description) (inferred from 100% identity to rpa:RPA0475)

Predicted SEED Role

"Putative NADP-dependent oxidoreductase PA1648"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (333 amino acids)

>TX73_002460 NADP-dependent oxidoreductase (Rhodopseudomonas palustris CGA009)
MTATVNRQILLIEKPKEKLGPEHFRLAESPIPEPKDGEALVKVRYISLDAANRAWMQGAT
YRAAVETDSVMPGGSVAEVVSSKAPGLVSGDLVFADTGWQDYAVLPAKHLAKLPKVEPMT
HLLSVYGIAGLTAYFGLLDIGKPRAGETVVVSAAAGSVGSIVGQIAKIKGCRVVGIAGGK
QKCDWLVNELGFDAAVDYKDGALFKALRAAAPNGIDVYFDNVGGDILEACLPQMNLKGRI
ACCGAVSQYDRTPSATGPRGIPGLIVVKRLIMQGFIVMDYMDQRDEAVAKLQEWVTSGKL
KVQEDVIDGLENTPQALIGLLAGENRGKRMVKV