Protein Info for TX73_002120 in Rhodopseudomonas palustris CGA009

Annotation: translational GTPase TypA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 607 TIGR00231: small GTP-binding protein domain" amino acids 2 to 147 (146 residues), 86.4 bits, see alignment E=1.9e-28 PF00009: GTP_EFTU" amino acids 2 to 194 (193 residues), 194.5 bits, see alignment E=3.4e-61 TIGR01394: GTP-binding protein TypA/BipA" amino acids 3 to 598 (596 residues), 911.9 bits, see alignment E=1.5e-278 PF03144: GTP_EFTU_D2" amino acids 217 to 288 (72 residues), 44.9 bits, see alignment E=3.3e-15 PF00679: EFG_C" amino acids 395 to 481 (87 residues), 78.2 bits, see alignment E=1e-25 PF21018: BipA_C" amino acids 484 to 592 (109 residues), 159.7 bits, see alignment E=4.8e-51

Best Hits

Swiss-Prot: 52% identical to TYPA_BACSU: GTP-binding protein TypA/BipA homolog (typA) from Bacillus subtilis (strain 168)

KEGG orthology group: K06207, GTP-binding protein (inferred from 100% identity to rpt:Rpal_0412)

Predicted SEED Role

"GTP-binding protein TypA/BipA" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (607 amino acids)

>TX73_002120 translational GTPase TypA (Rhodopseudomonas palustris CGA009)
MTLRNIAIIAHVDHGKTTLVDKLLQQSGTYRDNQRQVERAMDSNDLERERGITILAKCTS
VVWGDTHINIVDTPGHADFGGEVERILSMVDGVIVLVDAAEGPMPQTKFVVGKALKLGLK
PIVAINKVDRSDARVTEVVNEVFDLFAALDATDEQLDFPILYGSGKNGWMSDKPDGDPSE
GMKPLFELVLKHVHPPVVEEGPFRLLGTILEANPYLGRIITGRIASGSVKPNQAVKVLSR
DGKLVEQGRISKILAFRGLERVPLDIAEAGDIVAIAGLTKGTVADTFCDPAVDTPIQAQA
IDPPTVSMSFIVNNSPLAGTEGDKVTSRLIRDRLLREAEGNVALRVVESADKDAMEVSGR
GELQLAILIENMRREGFELSVSRPRVVLTRDENGQLLEPVEEVVIDVDEEFSGVVVQKMS
ERKAEMIEMRPSGGNRLRLVFYAPTRGLIGYQGELMTDTKGTAIMNRLFHNYLPYRGEIQ
GRRNGVLISNDQGEAVAYAMFKLEDRGPMMIEPGWKVYKGMIVGEHTRDNDLEINVLKGK
QLTNIRTTSKDEAVRLTPPIRMTLEKALAYIEDDELVEITPKSIRLRKRLLDPNERKRAE
KSKQAVA