Protein Info for TX73_002055 in Rhodopseudomonas palustris CGA009

Annotation: HD domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 197 PF12917: YfbR-like" amino acids 13 to 145 (133 residues), 34.5 bits, see alignment E=2.6e-12 PF13023: HD_3" amino acids 17 to 172 (156 residues), 143.8 bits, see alignment E=7.1e-46 PF01966: HD" amino acids 37 to 139 (103 residues), 30 bits, see alignment E=8.5e-11

Best Hits

KEGG orthology group: K07023, putative hydrolases of HD superfamily (inferred from 100% identity to rpt:Rpal_0400)

Predicted SEED Role

"HMP-PP hydrolase (pyridoxal phosphatase) Cof, detected in genetic screen for thiamin metabolic genes (PMID:15292217)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (197 amino acids)

>TX73_002055 HD domain-containing protein (Rhodopseudomonas palustris CGA009)
MLPANEIKGVLAFLREAERLKSVIRSGYTSTGRPESTAEHTWRLCLMAMLLADGLGDIDV
ARLLKICIVHDLGEALHGDVPAVAQVEGDDRAARERADIETLTQSLDDKRRAELLGLWHD
YETGASPEGRLAKGLDKLETILQHTQGLNPADFDYAFNLDYGARHTAVHPLVSAIRAELD
NDTRARMALQQASGAPH