Protein Info for TX73_001715 in Rhodopseudomonas palustris CGA009

Annotation: heat-inducible transcriptional repressor HrcA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 362 TIGR00331: heat-inducible transcription repressor HrcA" amino acids 20 to 359 (340 residues), 321.6 bits, see alignment E=3.9e-100 PF01628: HrcA" amino acids 124 to 346 (223 residues), 197.7 bits, see alignment E=2.5e-62

Best Hits

Swiss-Prot: 100% identical to HRCA_RHOPT: Heat-inducible transcription repressor HrcA (hrcA) from Rhodopseudomonas palustris (strain TIE-1)

KEGG orthology group: K03705, heat-inducible transcriptional repressor (inferred from 99% identity to rpx:Rpdx1_0297)

Predicted SEED Role

"Heat-inducible transcription repressor HrcA" in subsystem Heat shock dnaK gene cluster extended

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (362 amino acids)

>TX73_001715 heat-inducible transcriptional repressor HrcA (Rhodopseudomonas palustris CGA009)
MAQHDPIGLIAPNAGLAQLNERSREIFRQIVESYLATGEPVGSRNISRLISVPLSPASVR
NVMADLEQLGLIYAPHTSAGRLPTELGLRFFVDALMQIGDLTEPERQSIQAQLSSVGRAH
TVEAALGEALTRLSGLTRAAAVVLTAKANVRLKHIEFVRLEPERALVILVAEDGQVENRV
LTLPPGVPSSALIEAANYLNARIRGRTLAEARLELESLMVQNKAELDQLTQKVIAAGIAS
WSGGDGEDRQLIVRGHANLLEDLHALDDLERVRLLFDDLETKRGVIDLLGRAESADGVRI
FIGSENKLFSLSGSSTIIAPYSDGAGHIVGVLGVIGPTRLNYARVIPMVDYTARIVSRML
GG