Protein Info for TX73_001590 in Rhodopseudomonas palustris CGA009

Annotation: ATP-dependent protease ATPase subunit HslU

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 433 TIGR00390: ATP-dependent protease HslVU, ATPase subunit" amino acids 5 to 433 (429 residues), 620.6 bits, see alignment E=8.2e-191 PF07728: AAA_5" amino acids 52 to 88 (37 residues), 25 bits, see alignment 4.3e-09 PF00004: AAA" amino acids 53 to 102 (50 residues), 30 bits, see alignment 1.6e-10 amino acids 225 to 322 (98 residues), 29.6 bits, see alignment E=2.1e-10 PF07724: AAA_2" amino acids 191 to 319 (129 residues), 92.6 bits, see alignment E=7.2e-30 PF10431: ClpB_D2-small" amino acids 325 to 393 (69 residues), 23.4 bits, see alignment E=1.3e-08

Best Hits

Swiss-Prot: 100% identical to HSLU_RHOPA: ATP-dependent protease ATPase subunit HslU (hslU) from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)

KEGG orthology group: K03667, ATP-dependent HslUV protease ATP-binding subunit HslU (inferred from 100% identity to rpt:Rpal_0308)

Predicted SEED Role

"ATP-dependent hsl protease ATP-binding subunit HslU" in subsystem Proteasome bacterial or Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (433 amino acids)

>TX73_001590 ATP-dependent protease ATPase subunit HslU (Rhodopseudomonas palustris CGA009)
MTDFSPREIVSELDRFIVGQADAKRAVAIALRNRWRRLQLEGSLREEVLPKNILMIGPTG
VGKTEIARRLAKLAGAPFLKVEATKFTEVGYVGRDVEQIIRDLVEVAIAQVREKKRKDVQ
ARAQVAAEERVLDALVGPGSGPATRDSFRKKLRAGELNDKEIEIETQAGSGSPMFEIPGM
PGAQIGAVSLGDIFGKMGGRTKKRRLTVADSHEILVNEEADKLLDTDQLVQEAIAAVENN
GIVFLDEIDKICVRDGRSGGEVSREGVQRDLLPLIEGTTVSTKHGAVKTEHILFIASGAF
HIAKPSDLLPELQGRLPIRVELNALSRDDMRRILTEPEASLIKQYVALMKTEGVTLDFSD
DAIDALADVAVAVNSTVENIGARRLQTVMERVLDEISFVAPDRHGETFRVDADYVKTNVG
DLAKNTDLSRFIL