Protein Info for TX73_001490 in Rhodopseudomonas palustris CGA009

Annotation: diguanylate cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 557 signal peptide" amino acids 1 to 42 (42 residues), see Phobius details transmembrane" amino acids 292 to 311 (20 residues), see Phobius details PF02743: dCache_1" amino acids 107 to 275 (169 residues), 49.8 bits, see alignment E=4.9e-17 PF00672: HAMP" amino acids 313 to 361 (49 residues), 33.5 bits, see alignment 6.5e-12 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 376 to 541 (166 residues), 150.8 bits, see alignment E=1.4e-48 PF00990: GGDEF" amino acids 379 to 539 (161 residues), 161 bits, see alignment E=3.2e-51

Best Hits

KEGG orthology group: None (inferred from 100% identity to rpa:RPA0286)

Predicted SEED Role

"Phytochrome-like protein; Cph2"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (557 amino acids)

>TX73_001490 diguanylate cyclase (Rhodopseudomonas palustris CGA009)
MSRIAIVRKKAKLRALLGIRARLVVLALILVCPLMLDRVRLLEATRTAQLAAMANELSTL
AQRTADAEREVISSVEAVLKSAAYVHAAAAQAGRSCSILRASLRVDLPSIRMLMVAGPDG
VVHCSTSSMFVGSNISDRPYFRKALETHDFVVSDFLVGRQTQKGTILAAYPVSAIDTGEE
AVIVAGMNLDWLSDMMSSLAGRAGVNAALIDGEGTVLAAPPDERSLIGKKLDRLALLPAM
AETPQGRSSITMRDDAGRLMTVSRIPGTSARLVVTVDENKVSAGINHDIRTAYLQLALVC
LFVLLGALIAAERLIVQPISVLTGVAKKFAEGNWSARVARKRLPSEFVPLARAFNAMAAQ
LGQRERELVASNSRLTVMASMDLLSGLANRRGLQSRLDFEWMKGQQTGHRLALMMIDVDH
FKLFNDSYGHPEGDACLSRIGETLAAVADQTGGFAARYGGEEFCLLLPETGIGRALQVGE
LVRTTVEQLALPHKTSAFEHVTVSIGVACTLPSEHASPAELIEAADAALYAAKHRGRNNV
VEHGFIRASDGPVAMAS