Protein Info for TX73_001060 in Rhodopseudomonas palustris CGA009

Annotation: heme ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 244 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details transmembrane" amino acids 61 to 81 (21 residues), see Phobius details amino acids 93 to 112 (20 residues), see Phobius details amino acids 124 to 144 (21 residues), see Phobius details amino acids 155 to 174 (20 residues), see Phobius details amino acids 198 to 220 (23 residues), see Phobius details PF01578: Cytochrom_C_asm" amino acids 6 to 181 (176 residues), 141.9 bits, see alignment E=1.2e-45 TIGR01191: heme exporter protein CcmC" amino acids 42 to 225 (184 residues), 283.3 bits, see alignment E=4.5e-89

Best Hits

Swiss-Prot: 87% identical to CCMC_BRADU: Heme exporter protein C (cycZ) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: K02195, heme exporter protein C (inferred from 100% identity to rpt:Rpal_0202)

Predicted SEED Role

"Cytochrome c-type biogenesis protein CcmC, putative heme lyase for CcmE" in subsystem Biogenesis of c-type cytochromes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (244 amino acids)

>TX73_001060 heme ABC transporter permease (Rhodopseudomonas palustris CGA009)
MKLTELANPTRFLTLAGRLLPWLAAATALALAAGLTQGMLAPDDYQQGATVKIMFVHVPN
AWLAMFVWGVMSVASLGTLVWRHPLADVAAKTAAPIGAAFTFLALVTGSLWGRPMWGTYW
EWDARLTSMLVLFLMYLGLIALWRAVEDPSRAARAAAVLTLVGAVNLPIIKFSVDWWNTL
HQPASVVRMGGSTLDKAFLIPLLVTAIGFSLLFLTLHLAAMRNEILRRRVRSLQMMQASR
AEAA