Protein Info for TX73_000070 in Rhodopseudomonas palustris CGA009

Annotation: cation-translocating P-type ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 732 transmembrane" amino acids 103 to 126 (24 residues), see Phobius details amino acids 138 to 159 (22 residues), see Phobius details amino acids 171 to 193 (23 residues), see Phobius details amino acids 199 to 217 (19 residues), see Phobius details amino acids 355 to 376 (22 residues), see Phobius details amino acids 382 to 404 (23 residues), see Phobius details amino acids 678 to 695 (18 residues), see Phobius details amino acids 701 to 719 (19 residues), see Phobius details PF00403: HMA" amino acids 23 to 84 (62 residues), 38.4 bits, see alignment 2.1e-13 TIGR01511: copper-translocating P-type ATPase" amino acids 154 to 722 (569 residues), 556.8 bits, see alignment E=1.2e-170 TIGR01525: heavy metal translocating P-type ATPase" amino acids 173 to 720 (548 residues), 512.2 bits, see alignment E=4.5e-157 TIGR01494: HAD ATPase, P-type, family IC" amino acids 207 to 702 (496 residues), 231.9 bits, see alignment E=2.2e-72 PF00122: E1-E2_ATPase" amino acids 237 to 414 (178 residues), 158.4 bits, see alignment E=2.2e-50 PF00702: Hydrolase" amino acids 431 to 633 (203 residues), 94.4 bits, see alignment E=1.8e-30

Best Hits

Swiss-Prot: 75% identical to FIXI_BRADU: Nitrogen fixation protein FixI (fixI) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: K01552, [EC: 3.6.3.-] (inferred from 100% identity to rpa:RPA0013)

Predicted SEED Role

"Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4)" (EC 3.6.3.4)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-, 3.6.3.4

Use Curated BLAST to search for 3.6.3.- or 3.6.3.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (732 amino acids)

>TX73_000070 cation-translocating P-type ATPase (Rhodopseudomonas palustris CGA009)
MLQTRDFSHYVKDVDGRIAHLDLAVEGVHCASCMAKIERGLQSIPDVTLARVNLTDRRLA
VEWNKGSTLEPGQFIDRLAELGYKAYPYEPVRAEVEEAERTKFLLRCLGVAVFATMNVMM
LSVPVWYGGDLSPEARDFFHWLSALVALPCAAYAGQPFFQSAFRALKAKSVNMDVPITIG
ITLALGMSLVETINHAEHAYFDAAVMLIAFLLAGRFLDQKMRQKTRAVAGNLAALKAETA
TKFVGPDEISEVPIAAVRAGDIVLLRPGERCAVDGTVIEGRSEIDQSLITGETLYVPAER
GTQVYAGTLNISGTLRVRVDAAAEGTLLSEITRLLDHALQARSRYVRLADRASQLYAPVV
HATALLTIIGWVLAGASWHDAIVIGIAVLIITCPCALGLAIPAVQTVASGAMFRAGVLLN
AGDAIERAASVDTIVFDKTGTLTLPELDVVNAAGIPPEVFDLAGRLALASHHPVAAAVAR
AAHAKSPLPNVVEEPGRGVRTVFGGQELRLGSPAFCGADAEANQILSEDPEVSVVAFSRG
EQRVVFAVRQLLRPDAAKTIDALTNRGIAVELLSGDREPAVRHAAAALGVSAWRASVTPA
EKIAHIEALKKQGRIVMMVGDGMNDAPSLAAAHVSMSPISATHLSQATADLVFLGKELAP
VLAAVDYSRKAMAVMRENLGLAIGYNVLAVPIAIAGYATPLIAALAMSGSSLLVMLNAMR
ARRVRRGAAPWK