Protein Info for Synpcc7942_2534 in Synechococcus elongatus PCC 7942

Annotation: diguanylate cyclase with GAF sensor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 421 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF01590: GAF" amino acids 91 to 232 (142 residues), 67.8 bits, see alignment E=2.2e-22 PF13492: GAF_3" amino acids 92 to 234 (143 residues), 30.1 bits, see alignment E=8.7e-11 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 248 to 415 (168 residues), 157.5 bits, see alignment E=1.3e-50 PF00990: GGDEF" amino acids 254 to 412 (159 residues), 170.5 bits, see alignment E=3.9e-54

Best Hits

KEGG orthology group: None (inferred from 100% identity to syf:Synpcc7942_2534)

Predicted SEED Role

"Phytochrome-like protein; Cph2"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31K55 at UniProt or InterPro

Protein Sequence (421 amino acids)

>Synpcc7942_2534 diguanylate cyclase with GAF sensor (Synechococcus elongatus PCC 7942)
MLGLAAGLVVACLLAILKPGSGWLFLASGLASVSVASFLQAASDRRYLDDLSHRYEQLHD
EKEILEENYQKQLAQERILLDITLNIRQSLNLSQVMETAVSEVRSLLRVNRVLIYQFQPD
WRGLIVAESVSEPEFSLMGIQIEDYCFANNWDQQYRDGYIHQIDHVAIAGLDDCYRRLLQ
SIKVKANLVLPIRYGDSLWGLLAAHHCILPRTWRNSEVVLLTQVAEQLSIAIAQSQLLKT
LQVTNQRLQDQVRIDGLTQIPNRRRFDEYFNDVWLWGCRDHTPVALLLIDVDYFKTYNDF
YGHLAGDEVLRKIGLLLNSVVLRATDLVARYGGEEFVAVLPSTTLEGAQAVARRLQADLQ
RLQIPHNHSPVAAWVTVSIGIAVTIPTIDVALTDLIDQADKALYEAKSAGRNCIMWAESL
A