Protein Info for Synpcc7942_2312 in Synechococcus elongatus PCC 7942

Name: murG
Annotation: UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 357 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 65 to 83 (19 residues), see Phobius details amino acids 95 to 117 (23 residues), see Phobius details TIGR01133: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase" amino acids 7 to 352 (346 residues), 275.9 bits, see alignment E=2.3e-86 PF03033: Glyco_transf_28" amino acids 9 to 141 (133 residues), 116.4 bits, see alignment E=1.1e-37 PF04101: Glyco_tran_28_C" amino acids 183 to 323 (141 residues), 125.9 bits, see alignment E=1.7e-40

Best Hits

Swiss-Prot: 100% identical to MURG_SYNP6: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (murG) from Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1)

KEGG orthology group: K02563, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC: 2.4.1.227] (inferred from 100% identity to syf:Synpcc7942_2312)

Predicted SEED Role

"UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (EC 2.4.1.227)" in subsystem Peptidoglycan Biosynthesis (EC 2.4.1.227)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.227

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31KS7 at UniProt or InterPro

Protein Sequence (357 amino acids)

>Synpcc7942_2312 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (Synechococcus elongatus PCC 7942)
VSVAQPRLLFAASGTGGHVFPALAVAEALPEAKIDWLGVPDRLETQLVGDRYPLHTIRVG
GFQGSWLLRPLTALRLIGAIFKVRRLLKRQQIEAVFTTGGYIAGPAIAAAWSLGIPVVLH
ESNALPGKTTRLLSRFCRRVALGFAEAGEYLPGRPLQVVGTPLRSQFYQPSQHGLPIPEN
VPVLLVMGGSQGAVAINRLVRAAAPAWLAAGLWIVHLTGQQDPDRGQLQHPQYIELSFVD
NVAPLLNRADFSISRAGAGSLAELAAAGLPSLLIPYPFAAEDHQTFNARIFAKAGAAILA
PQSELTVEQLQQQILDLLRARLGAAIANPLPKMAAAAGKLHVADSAEQVANLLRSLL