Protein Info for Synpcc7942_1965 in Synechococcus elongatus PCC 7942

Name: ppx
Annotation: exopolyphosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 549 PF02541: Ppx-GppA" amino acids 36 to 333 (298 residues), 274.7 bits, see alignment E=1.5e-85 PF21447: Ppx-GppA_III" amino acids 346 to 524 (179 residues), 152.6 bits, see alignment E=1.5e-48 PF01966: HD" amino acids 364 to 460 (97 residues), 31.4 bits, see alignment E=3.1e-11

Best Hits

KEGG orthology group: K01524, exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC: 3.6.1.11 3.6.1.40] (inferred from 100% identity to syf:Synpcc7942_1965)

Predicted SEED Role

"Exopolyphosphatase (EC 3.6.1.11)" in subsystem Phosphate metabolism (EC 3.6.1.11)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.11 or 3.6.1.40

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31LS4 at UniProt or InterPro

Protein Sequence (549 amino acids)

>Synpcc7942_1965 exopolyphosphatase (Synechococcus elongatus PCC 7942)
MSTEIAPHARPALPSELGPEPILAAIDVGTNSIHMVVVQIRPDLPAFDIVGTEKATVRLG
DRDPATGELTEAAMERALQALQRCRAIAAARGATQIVAVATSAVREAPNGRQFLERVIHE
VGLEVDLISGPEEARRIYLGVLSGMDFQQRHHAIIDIGGGSTELILGAGQEPLCLTSTKV
GAVRLTQEFIHTDPISPSEYTVLQAYVRGMVERAVDEVKAALPPNTPLRLIGTSGTIQAL
AALHAHQSQGSLPTTFNGYSLALGDLQQLVQQLRRMPFAERQTLPELSERRAEIIVAGAI
VLQETMQLLGCDRVTICERALREGLIVDWMLSHGLIEDKLRYQGSVRQRSVYNQARKFRV
DVSHGEQVAQLALSLFDQLRGQLHQWGESERELLWAAAILHNCGHHIDHSSHHKHSYYLI
RHGGLLGYNETEIELIANLARYHRKSLPKKKHENFRTLPTKEQRRLVEQLSAILRAAVAL
DRRQVGAIASLHCRYLAPQRQLLLQLHPARTSEDCALELWSFDYNRHALEAAFAINVAAE
LVPQPLSAV