Protein Info for Synpcc7942_1669 in Synechococcus elongatus PCC 7942

Name: kdpB
Annotation: potassium-transporting ATPase subunit B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 696 transmembrane" amino acids 49 to 67 (19 residues), see Phobius details amino acids 82 to 101 (20 residues), see Phobius details amino acids 236 to 260 (25 residues), see Phobius details amino acids 269 to 293 (25 residues), see Phobius details amino acids 603 to 624 (22 residues), see Phobius details amino acids 630 to 649 (20 residues), see Phobius details amino acids 668 to 690 (23 residues), see Phobius details TIGR01497: K+-transporting ATPase, B subunit" amino acids 26 to 690 (665 residues), 1095.4 bits, see alignment E=0 TIGR01494: HAD ATPase, P-type, family IC" amino acids 92 to 615 (524 residues), 237.6 bits, see alignment E=2e-74 PF00122: E1-E2_ATPase" amino acids 123 to 301 (179 residues), 110.6 bits, see alignment E=1e-35 PF00702: Hydrolase" amino acids 318 to 546 (229 residues), 89.3 bits, see alignment E=6.8e-29

Best Hits

Swiss-Prot: 74% identical to KDPB_SYNY3: Potassium-transporting ATPase ATP-binding subunit (kdpB) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K01547, K+-transporting ATPase ATPase B chain [EC: 3.6.3.12] (inferred from 100% identity to syf:Synpcc7942_1669)

MetaCyc: 61% identical to K+ transporting P-type ATPase subunit KdpB (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-2 [EC: 7.2.2.6]

Predicted SEED Role

"Potassium-transporting ATPase B chain (EC 3.6.3.12) (TC 3.A.3.7.1)" in subsystem Potassium homeostasis (EC 3.6.3.12, TC 3.A.3.7.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.12

Use Curated BLAST to search for 3.6.3.12 or 7.2.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31MM0 at UniProt or InterPro

Protein Sequence (696 amino acids)

>Synpcc7942_1669 potassium-transporting ATPase subunit B (Synechococcus elongatus PCC 7942)
MSVLSRHHRAPGGPRSQRRHLAQPQRQGLYRRAFFEAFRKLDPRQVVRNPVMFVVWLGTV
LTFLLVLDPGLFGSSNEPGARSFNALICLTLFLTVWFANAAEAIAEGRGKAQADALRATQ
TQTLARRLTAGGTVESVNSPELRKGDRVVVAAGEMIPADGEVIAGVASVDESAITGESAP
VLKEAGSDVASSVTGGTRVISDQLTIQITSEPGKGFIDRMIQLVEGAKRSKTPNEIALTV
LLAVLTQIFLIAIATLSPIATYLGSPTPVATLIALLVALIPTTIGGLLSAIGIAGMDRVA
QFNVIATSGRAVEACGDINTLVLDKTGTITLGNRLADSFISLAGRSPADVARAAWIASYF
DNTPEGKSIVRLAESQLGQLDFDWPSTTGIDFSARTRMSGTDTSDGQEFRKGAVDAIKGF
ARSRGGSIPADLDAAFEQISRLGGTPLAVCIDSEIYGVIYLKDIIKTGIRERFDQLRRMG
IRTVMLTGDNHLTASVIAAEAGVDDFIAEATPEDKIAVIQAEQSQGKLVAMTGDGTNDAP
ALAQANVGLAMNSGTQAAKEAANMVDLDSDPTKLIDVVTIGKQLLITRGALTTFSIANDV
AKYFAILPALFINAGLAPLNVMGLATPRSALLAAMLYNALIIPALIPLALKGVKFRPLTA
NELLQRNLLIYGLGGLIAPFLAIKAIDSVIVRSGIL