Protein Info for Synpcc7942_1550 in Synechococcus elongatus PCC 7942

Name: umuC
Annotation: DNA-directed DNA polymerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 418 PF00817: IMS" amino acids 5 to 148 (144 residues), 131.1 bits, see alignment E=4.9e-42 PF11799: IMS_C" amino acids 238 to 351 (114 residues), 78.1 bits, see alignment E=1e-25 PF13438: DUF4113" amino acids 362 to 411 (50 residues), 80.5 bits, see alignment 1.1e-26

Best Hits

Swiss-Prot: 43% identical to SAMB_SALTM: Protein SamB (samB) from Salmonella typhimurium

KEGG orthology group: K03502, DNA polymerase V (inferred from 100% identity to syc:syc0008_d)

Predicted SEED Role

"Error-prone, lesion bypass DNA polymerase V (UmuC)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31MY9 at UniProt or InterPro

Protein Sequence (418 amino acids)

>Synpcc7942_1550 DNA-directed DNA polymerase (Synechococcus elongatus PCC 7942)
MFALIDCNNFYVSCERVFDPKLQGQPVVVLSNNDGCVIARSAEAKALGIPMGIPFFKVKD
LISQHQIQVFSSNYALYGDMSQRVMQTLATLCPDLEVYSIDEAFLDFSGFQAQPLQQGQL
IRQTVGQWTGIPVSIGIAATKVLAKVANKLAKQNGGVFVLSPSKVQAVLMTLPVEEVWGI
SSRWGQRLRALNISTAAELQATNLNLMRQQFNIVLERIVRELRGESCLPLESIVNPQQSL
VVSRSFGQPITTLPELKQAVATYVSRAAEKLRSRQLTTSYLTVFVRTNRFQENYEAPNAS
QGLLTPTNHTGKLLEIALRCTESLYQPGRAYKKAGVLFQGLGSAQSIQQSLFEESDSEKG
AALMVTMDRLNRRYGRQSLHYGATGTRQPWAMRSDQRSPQYTTRWQDLPEVHARAREI