Protein Info for Synpcc7942_1473 in Synechococcus elongatus PCC 7942

Name: ndhD5
Annotation: putative monovalent cation/H+ antiporter subunit D

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 480 transmembrane" amino acids 6 to 22 (17 residues), see Phobius details amino acids 29 to 48 (20 residues), see Phobius details amino acids 68 to 87 (20 residues), see Phobius details amino acids 94 to 111 (18 residues), see Phobius details amino acids 117 to 136 (20 residues), see Phobius details amino acids 148 to 168 (21 residues), see Phobius details amino acids 186 to 208 (23 residues), see Phobius details amino acids 219 to 241 (23 residues), see Phobius details amino acids 247 to 265 (19 residues), see Phobius details amino acids 272 to 288 (17 residues), see Phobius details amino acids 293 to 314 (22 residues), see Phobius details amino acids 328 to 348 (21 residues), see Phobius details amino acids 360 to 381 (22 residues), see Phobius details amino acids 400 to 420 (21 residues), see Phobius details amino acids 432 to 450 (19 residues), see Phobius details amino acids 462 to 479 (18 residues), see Phobius details PF00361: Proton_antipo_M" amino acids 115 to 376 (262 residues), 125.7 bits, see alignment E=1.1e-40

Best Hits

KEGG orthology group: K05568, multicomponent Na+:H+ antiporter subunit D K05575, NADH dehydrogenase I subunit 4 [EC: 1.6.5.3] (inferred from 100% identity to syf:Synpcc7942_1473)

Predicted SEED Role

"Na(+) H(+) antiporter subunit D" in subsystem Sodium Hydrogen Antiporter

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31N66 at UniProt or InterPro

Protein Sequence (480 amino acids)

>Synpcc7942_1473 putative monovalent cation/H+ antiporter subunit D (Synechococcus elongatus PCC 7942)
MKELTLIWIFSPFLLGFLAYILPNTSRLLALLAAIASAAYAGKLFLGGTAVDFRFLDQFG
IDLILDPLAAFFILTNALVTTAVVCYCWKSNKTAFFYTQLLILHGSVNAAFACADFMSLY
VALEVLSIATFLLISYPRNDRSIWIGLRYLFVSNVAMLFYLVGTILVYQANHSFAFQGLQ
NAPLEAIALIFMALLVKGGIFVSGFWLPLTHSESEAPVSALMSGVVVKAGILPLVRCALL
FEAVDQIIRIFGVATALLGVFYAVLEKDTKRILAFHTISQVGFILAAPEVGGFYALSHGL
VKAALFLIAGILPSRNIKELQLQPIPNSIWIVLVIASFSISGFPLLSGFGAKVLTMKNLL
PWQVIGMNLAAVGTAISFAKFIFLPHQQESSTERLSQKQGFWIAMTLLLGGLLVANIVYY
EAYTLENILKPLATIVIGWIAYLVIFRRLVIKLPRAIEQFENLIGVMIISLVVIFGIVAV