Protein Info for Synpcc7942_1298 in Synechococcus elongatus PCC 7942

Annotation: diguanylate cyclase (GGDEF domain)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 576 transmembrane" amino acids 38 to 61 (24 residues), see Phobius details amino acids 199 to 220 (22 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 402 to 571 (170 residues), 140.9 bits, see alignment E=1.6e-45 PF00990: GGDEF" amino acids 407 to 569 (163 residues), 130.1 bits, see alignment E=3.5e-42

Best Hits

KEGG orthology group: None (inferred from 100% identity to syc:syc0255_c)

Predicted SEED Role

"Sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31NP1 at UniProt or InterPro

Protein Sequence (576 amino acids)

>Synpcc7942_1298 diguanylate cyclase (GGDEF domain) (Synechococcus elongatus PCC 7942)
MQNAFSTADSSDQSLLDEIEVGLPNPKPRLKVKGWRSWVYGGAGLLLGVFGIAGSLGLFA
IQEARRQVDRSLEAIEVAQIIDYYQIQLLFRFNSYLESRQETDNKLYQLGQEQLLDSIDK
LKSFYVQPPNPEQLKEIAALSALIQSKLEEQQNLMNAKQEATPSLDASYYNVHSQINQIV
QNERRILDRRVINVDSYRLLTNVLLILGSLLGLTLAIALYQEQRREQREMSVIDHDYQEK
EDTLNHKLKVLQLEQKLSSLLLTCRSTEEIKKILEDFFQRWFPQAQGAVLEISASRDTLV
EIARFGELELPSLAMPSDCWAMRRGECYHSSQAEFTYPCGLCHHLHGEIIPDNIICIPLQ
AHEQLIGILHLTNVDPKSQKIVESFGQQLALPLAVMHLQEQLKQLSYRDSNTALYNRRFL
DEILERTLLTAIRRNESRSLGDAPYSVGLIFLDVDKFKDFNTRFGHAVGDQVLQTLGQTM
LESCRRGEDLACRYGGEEFVLILPGMDEDMTYQRAEQIRLAVSQKAVSNCRITISLGVAA
FPSAGQTPSELLKAANMAMLKAKLNGRNQTVRISQL