Protein Info for Synpcc7942_1094 in Synechococcus elongatus PCC 7942

Annotation: putative transcriptional activator, TenA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

KEGG orthology group: K03707, thiaminase (transcriptional activator TenA) [EC: 3.5.99.2] (inferred from 100% identity to syc:syc0455_d)

Predicted SEED Role

"Thiaminase II (EC 3.5.99.2)" in subsystem Thiamin biosynthesis (EC 3.5.99.2)

MetaCyc Pathways

base-degraded thiamine salvage (1/2 steps found)
thiamine diphosphate salvage IV (yeast) (4/7 steps found)

KEGG Metabolic Maps

Thiamine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.99.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31P95 at UniProt or InterPro

Protein Sequence (205 amino acids)

>Synpcc7942_1094 putative transcriptional activator, TenA family (Synechococcus elongatus PCC 7942)
VSLADRLWQQNQALVAEIRVHPFVVALVKGSLPLTNFQTYIGQDAFFLEAFARAYSIAAA
KSANQQDFEQFHQLADGILAELKLHASLATRWQIDLRSVQPNPATHRYVDFLTAIAWSQP
LGAIAAAMVPCMRLYADLGQFWSQRGYAPQPYGEWVETYADPAFDSLAQQLEALLDRHGT
EAIAAEPYTYALTCERDFFSAVGTA