Protein Info for Synpcc7942_1079 in Synechococcus elongatus PCC 7942

Name: recG
Annotation: ATP-dependent DNA helicase RecG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 817 PF17191: RecG_wedge" amino acids 126 to 301 (176 residues), 71.6 bits, see alignment E=1.5e-23 TIGR00643: ATP-dependent DNA helicase RecG" amino acids 143 to 782 (640 residues), 801.7 bits, see alignment E=2.9e-245 PF04851: ResIII" amino acids 392 to 550 (159 residues), 33.2 bits, see alignment E=1.2e-11 PF00270: DEAD" amino acids 396 to 555 (160 residues), 83.7 bits, see alignment E=3.3e-27 PF00271: Helicase_C" amino acids 598 to 706 (109 residues), 65.1 bits, see alignment E=1.6e-21 PF19833: RecG_dom3_C" amino acids 735 to 796 (62 residues), 53.1 bits, see alignment 7.1e-18

Best Hits

Swiss-Prot: 66% identical to RECG_SYNY3: ATP-dependent DNA helicase RecG (recG) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K03655, ATP-dependent DNA helicase RecG [EC: 3.6.4.12] (inferred from 100% identity to syf:Synpcc7942_1079)

Predicted SEED Role

"ATP-dependent DNA helicase RecG (EC 3.6.1.-)" in subsystem DNA-replication (EC 3.6.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.-, 3.6.4.12

Use Curated BLAST to search for 3.6.1.- or 3.6.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31PB0 at UniProt or InterPro

Protein Sequence (817 amino acids)

>Synpcc7942_1079 ATP-dependent DNA helicase RecG (Synechococcus elongatus PCC 7942)
MTAASPAPDWRRLQQALAIEAEQGFGDLVGRQARFSEFLSQALQEAATAIADERWQQLAQ
AYQRYGDLSASQRQHLVANTRRQIHEQQRRSQARVSENSPPVRRLPRSQSPVATTTGQMA
LDQALTYLKGVGPRVAAQLERLELRTVRDLLHHYPRNYVDYARQVNIRALEPGETATLIG
AVQRCTCFTSPRNAKLTILELVVRDGSGQLRLSRFFMGTRYSGRGWQEQQRRLYPPGTMI
AASGLVKRSKYGVTLDNPEIEVLDSPDSPIASLKVGRIVPIYPLTEGVAADTLRRAIVQA
LPAAEQLRDPLPTVLREQHQLLVLNQAIAAIHFPETPELLQQARRRLVFDEFLYLQLGLL
QRRARQRAAAAAAVLAPTGELIDRFYQLLPFQLTGAQQRVVNDILTDLQQPWPMNRLVQG
DVGSGKTVVAIVSLLAAIQAGYQGALMAPTEVLAEQHYRKLVDWCTQLHLPVELLTGSTR
AAKRREIQRSLATGELPLLVGTHALIQDPVDFQNLGLVVIDEQHRFGVAQRAKLQQKGVN
PHVLTMTATPIPRTLALTLHGDLEVSQIDELPPGRQPIQTTALGPSDRHHAHDLMRREIA
QGRQVYVVLPLVEESEKLDLRSAIEEYQRLSQVFPEFQIGLLHGRMSSAEKDAAIAAFRD
RQTDILVSTTVVEVGVDVPNATVMLIEHAERFGLSQLHQLRGRVGRGAARSYCLLMSASR
SETAQQRLKVMEQSQDGFFIAEMDLRLRGPGQVLGTRQSGLPDFALASLVEDQDVLDLAR
TTAEQLIEQDPELTRSPLLKQELEARYRRLMGGMILT