Protein Info for Synpcc7942_1020 in Synechococcus elongatus PCC 7942

Name: menC
Annotation: O-succinylbenzoate synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01927: o-succinylbenzoate synthase
  • amino acids 9 to 302 (294 residues), 216.4 bits, E=2.9e-68
• PF21508: MenC_N
  • amino acids 22 to 93 (72 residues), 33.5 bits, E=4e-12
• PF13378: MR_MLE_C
  • amino acids 125 to 290 (166 residues), 50 bits, E=3.3e-17

Best Hits

KEGG orthology group: K02549, O-succinylbenzoate synthase [EC: 4.2.1.113] (inferred from 100% identity to syc:syc0526_c)

Predicted SEED Role

"O-succinylbenzoate synthase (EC 4.2.1.113)" (EC 4.2.1.113)

MetaCyc Pathways

• superpathway of menaquinol-9 biosynthesis (10/10 steps found)
• superpathway of demethylmenaquinol-9 biosynthesis (9/9 steps found)
• 2-carboxy-1,4-naphthoquinol biosynthesis (7/7 steps found)
• superpathway of menaquinol-10 biosynthesis (9/10 steps found)
• superpathway of menaquinol-11 biosynthesis (9/10 steps found)
• superpathway of menaquinol-12 biosynthesis (9/10 steps found)
• superpathway of menaquinol-13 biosynthesis (9/10 steps found)
• superpathway of menaquinol-6 biosynthesis (9/10 steps found)
• superpathway of menaquinol-7 biosynthesis (9/10 steps found)
• superpathway of menaquinol-8 biosynthesis I (9/10 steps found)
• superpathway of demethylmenaquinol-6 biosynthesis I (8/9 steps found)
• superpathway of demethylmenaquinol-8 biosynthesis I (8/9 steps found)
• superpathway of phylloquinol biosynthesis (12/15 steps found)
• superpathway of chorismate metabolism (40/59 steps found)

KEGG Metabolic Maps

• Ubiquinone and menaquinone biosynthesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.2.1.113

Sequence Analysis Tools

See Q31PG9 at UniProt or InterPro

Protein Sequence (316 amino acids)

>Synpcc7942_1020 O-succinylbenzoate synthase (Synechococcus elongatus PCC 7942)
MSFRFAFRPYQRRLRQPLRTARDAQITVRLGIWLRLETDTEVRWGEIAPWPSFGSETLAE
AIAFCEAFPPDPEWEDLATAPDSLPACQFGFGCLRESNATDFLPTSAVLLPAGAAALTAI
ATASPATTYKWKIGLDLESELDLLPQLDRLLPSAAKLRLDANGGLTKAQADRLLQVLTAI
NERRSGRIEWLEQPLDPSQVDDLLQLVQDWPLVAIALDESVSQLSSLQFWQAQGWPGLYV
LKPAIAGWPQTVRQFCQVHHLPVVVSSMFESPIGWRAVAAIAAQLGRADQAQGLGTTAWF
TDDWESKTAAALWQHP