Protein Info for Synpcc7942_0580 in Synechococcus elongatus PCC 7942

Name: ftsI
Annotation: Peptidoglycan glycosyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 605 transmembrane" amino acids 21 to 42 (22 residues), see Phobius details TIGR03423: penicillin-binding protein 2" amino acids 22 to 585 (564 residues), 600.7 bits, see alignment E=1.6e-184 PF03717: PBP_dimer" amino acids 67 to 235 (169 residues), 173 bits, see alignment E=8.7e-55 PF00905: Transpeptidase" amino acids 269 to 581 (313 residues), 204.1 bits, see alignment E=3e-64

Best Hits

KEGG orthology group: K05515, penicillin-binding protein 2 (inferred from 100% identity to syf:Synpcc7942_0580)

Predicted SEED Role

"Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129)" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Flagellum in Campylobacter or Peptidoglycan Biosynthesis (EC 2.4.1.129)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129

Use Curated BLAST to search for 2.4.1.129

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31QQ7 at UniProt or InterPro

Protein Sequence (605 amino acids)

>Synpcc7942_0580 Peptidoglycan glycosyltransferase (Synechococcus elongatus PCC 7942)
MANPTFGNRDSGRSVGRSYQSLWLLLGITTVFFGALGGRLAYMQIQQGERNRELANENRI
HLLPRLPERGRILDREGRVLASSRHVYSLYVWPLAIKDDRWPDTRRRLAELLKVPESTLQ
ARIDRQKDNAAYRVRLAQNLSQPQVIAFEENRRNFIGVEVDYDSVRYYPNGSIAAHVLGY
TGEISDEELKRREEQGYRPGDVIGQAGLEAAFEKQLRGEWGGQQVEVDALGNVVRILGDK
QARAGKDVTITLDLDLQKAAEAAIGNSMGAIVAIDPRDGSILAMVSRPTYDPNVFATEIS
QAEWDRLQQLEFPFVNRALQSFPPASTFKIVTTAAALESGKYSPDTVLQTFPFLRVGGIQ
FWDWNNAGFGPLGFVGAMRYSSDTFFYQVAQRIGGDAIAAMCRRFGMGQRTGVELAAEEG
RGLVPDKAWKLKNLNEEWTVGDSINMSIGQGFLLQTPLQVAVMFAIPANNGFRVKPHFLK
DDRDSKEWREDLKLKPSTMKVIRDGLVSVVADGTGAALRVPSLPPNAGKTGTAEDPPRRS
HTWYGGYAPIEKPEIVVVSFNENSGGGGGSTAAPKVRQVMEAYFRKKALRAQAAKGKQPS
ANTSQ