Protein Info for Synpcc7942_0480 in Synechococcus elongatus PCC 7942

Annotation: GAF sensor signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 577 PF13492: GAF_3" amino acids 165 to 293 (129 residues), 42.9 bits, see alignment E=1.2e-14 PF00512: HisKA" amino acids 335 to 401 (67 residues), 75.1 bits, see alignment E=7.2e-25 PF02518: HATPase_c" amino acids 449 to 571 (123 residues), 85 bits, see alignment E=1e-27

Best Hits

KEGG orthology group: None (inferred from 100% identity to syf:Synpcc7942_0480)

Predicted SEED Role

"Circadian input kinase A / Phytochrome-like protein" in subsystem Cyanobacterial Circadian Clock

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q31R07 at UniProt or InterPro

Protein Sequence (577 amino acids)

>Synpcc7942_0480 GAF sensor signal transduction histidine kinase (Synechococcus elongatus PCC 7942)
MSGSASRSTAANPLELAWITPSAAQLASTADLYYVQDLLGRYLSFAWRSGQWLGLNSEQV
VGSYLSEQFTPVDLNLYLARMRRAMHRGRAEQFRTGFRFQGQVYVFDLTLSPILQPQQAS
TLLLVIGRQQEPLPEALPEPPIAIAPPHHAKLFAQIAWDIRRTLDPETIWRHTVQGLGQA
LGLQRCLLCPYELGSTAIAIVAEYRQAHLPVVLGEQLAIARNPSLADALLSLRPTQAVVD
FERSPAEPIWMVPTGYQDHPNGVLLLRSAEELTAGDRDLVWELADQVGTALAHARLYAQS
QALALELQRANQTLLEQQQALIEAHRQSEALSQLKTDFLANTSHELRTPLTGMIGYLQLL
QDDLAETPEERQEFIAGAYHSALHLLGIINDILDIARIEAGRLQLQAETVPLRNLLAEVE
TCLRSQAQAKGLVYRCRIAAETESVALWGDRQRLLQVLFNLVGNAIKFTLTGYVEVRATA
VWQPLCANGQNLPGYLRLEIEDSGIGVAPERQGSLFQPFSQADSSLTRQFGGSGLGLVIC
RRLLESMGGIVELFSPGEGLGTTVTCLIPLAPAIIPS