Protein Info for SMc04436 in Sinorhizobium meliloti 1021

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 75 92 PF05016: ParE_toxin" amino acids 9 to 87 (79 residues), 58 bits, see alignment E=6.1e-20 TIGR02385: addiction module toxin, RelE/StbE family" amino acids 10 to 86 (77 residues), 35.3 bits, see alignment E=6.5e-13

Best Hits

Swiss-Prot: 63% identical to RELE_SHIFL: mRNA interferase RelE (relE) from Shigella flexneri

KEGG orthology group: K06218, RelE protein (inferred from 100% identity to sme:SMc04436)

MetaCyc: 63% identical to Qin prophage; mRNA interferase toxin RelE (Escherichia coli K-12 substr. MG1655)
3.1.26.-

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q92Q75 at UniProt or InterPro

Protein Sequence (92 amino acids)

>SMc04436 hypothetical protein (Sinorhizobium meliloti 1021)
MRFGYRRGLEFLPSARKEWDKLGATIRQQLVKKLRERLERPRIPSAALHGMPDHYKIKLR
QLGYRLVYRVDDGSVTVLVVAVGKRERVTSTT